PRIMARY BILIARY CHOLANGITIS
Clinical trials for PRIMARY BILIARY CHOLANGITIS explained in plain language.
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New hope for PBC patients: phase 3 trial of saroglitazar launches
Disease control Not yet recruitingThis study tests a new drug, saroglitazar magnesium, in 89 adults with primary biliary cholangitis (PBC) who did not get enough benefit from or could not tolerate standard treatment (UDCA). The goal is to see if the drug can lower a key liver enzyme (alkaline phosphatase) to norm…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New hope for rare liver disease: drug aims to slow damage
Disease control Not yet recruitingThis long-term study tests whether saroglitazar magnesium can prevent serious liver complications in people with primary biliary cholangitis (PBC), a rare autoimmune liver disease. About 386 adults already on standard treatment will receive either the drug or a placebo. The goal …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New blood test method for liver disease could make diagnosis easier
Diagnosis Not yet recruitingThis study checks if a simpler way to collect blood samples works as well as the standard method for the HepQuant DuO liver test. The test involves drinking a natural substance and taking blood samples 20 and 60 minutes later. Researchers will compare different blood collection t…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: HepQuant, LLC • Aim: Diagnosis
Last updated Jun 27, 2026 11:02 UTC
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New strip drug targets debilitating itch in rare liver disease
Symptom relief Not yet recruitingThis Phase 2a trial tests TH104, a nalmefene strip placed inside the cheek, for moderate to severe itching in primary biliary cholangitis (PBC). About 40 adults with PBC will receive either TH104 or a placebo to see if it safely reduces itch. The study is not yet recruiting.
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2 • Sponsor: Tharimmune Inc • Aim: Symptom relief
Last updated Jun 26, 2026 15:06 UTC
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800-Patient study aims to unlock secrets of autoimmune liver disease
Knowledge-focused Not yet recruitingThis French study will collect medical data and biological samples from 800 people with autoimmune liver diseases. Researchers hope to identify new markers that explain why some patients respond well to treatment while others do not. The goal is to better understand the immune me…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Spleen scan could spare PBC patients unnecessary scopes
Knowledge-focused Not yet recruitingThis study looks at whether measuring spleen stiffness with a simple ultrasound-like test (FibroScan) can help doctors better predict complications in people with Primary Biliary Cholangitis (PBC). Researchers will follow 125 adults already on standard treatment, adding a spleen …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC