POLYPHARMACY
Clinical trials for POLYPHARMACY explained in plain language.
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Could a better medication review keep older adults out of the hospital?
Disease control CompletedThis trial tests whether a structured medication review and care coordination (TMPC) can reduce drug-related hospital readmissions in adults aged 70 and older who take five or more regular medications. Participants receive a detailed medication analysis, discussions among hospita…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New program aims to cut risky pill overload in seniors
Disease control CompletedThis study tested a program to help older adults (70+) who take 5 or more medications reduce their pill burden safely. Participants worked with a pharmacist and their family doctor to pause or lower doses of unnecessary drugs, focusing on what matters most to the patient. The goa…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: McMaster University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Video visits with pharmacists may cut risky drug use in older veterans
Disease control CompletedThis study tested whether a pharmacist-led video visit to the home could improve medication use in older Veterans taking many daily drugs. 304 Veterans with at least 2 chronic conditions and 5 daily medications took part. The goal was to reduce potentially inappropriate medicatio…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New program aims to cut unnecessary pills for dementia patients
Symptom relief CompletedThis study tested a program where a pharmacist worked with people living with dementia, their care partners, and their doctors to review and reduce unnecessary medications. The goal was to simplify medication routines and lower treatment burden. The study included 138 participant…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Could cutting pills boost quality of life for dementia patients?
Symptom relief CompletedThis pilot study tested a program called Shed-MEDS that helps safely reduce or stop unnecessary medications in assisted living residents with dementia. The goal was to see if cutting back on meds could improve quality of life. Eighteen residents took part, and researchers tracked…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Can a simple DNA test make medications safer for seniors?
Knowledge-focused CompletedThis study looked at whether a DNA test (pharmacogenomics) could help doctors choose the right medications for older adults taking five or more drugs. Researchers tested 66 participants and measured how often the results led to medication changes. The goal was to see if this appr…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: Geisinger Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Hospital help: does a drug coordinator cut risky pill use?
Knowledge-focused CompletedThis study tested whether a medication coordinator could help patients avoid risky or unnecessary drugs after leaving the hospital. 141 patients who took at least five medicines took part. The coordinator worked with patients to review their medications and create a personal plan…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: University of Southern Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Talking less meds: training helps doctors cut pills for seniors
Knowledge-focused CompletedThis study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Study reveals what happens when your doctor keeps changing
Knowledge-focused CompletedThis study interviewed 26 older adults (75+) with chronic illnesses who take many medications. Researchers wanted to understand how patients feel about being cared for by the same doctor over time, and what happens when they lose that regular doctor. The goal was to learn about t…
Matched conditions: POLYPHARMACY
Sponsor: IBS Granada • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New program helps dementia patients ditch unneeded pills
Knowledge-focused CompletedThis study tested whether a pharmacist-led program could help older adults with dementia and their caregivers reduce unnecessary medications. The program included an educational brochure, a telehealth visit with a pharmacist, and tailored recommendations for the patient's doctor.…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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VA study tests new methods to improve care for sleep, blood thinners, and risky medications
Knowledge-focused CompletedThis study looked at how to help busy doctors at VA clinics adopt better treatments for three common issues: reducing risky medications in older adults, using blood thinners more safely, and offering talk therapy for insomnia instead of sleep pills. Researchers compared two diffe…
Matched conditions: POLYPHARMACY
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC