Could a better medication review keep older adults out of the hospital?

NCT ID NCT05899114

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This trial tests whether a structured medication review and care coordination (TMPC) can reduce drug-related hospital readmissions in adults aged 70 and older who take five or more regular medications. Participants receive a detailed medication analysis, discussions among hospital and community doctors, and a patient interview. The study compares this approach to usual care to see if it lowers readmissions within 30 days and is cost-effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transitional Multidisciplinary Pharmacotherapeutic Care (TMPC) - a structured medication review with care coordination

What this could lead to

If effective, this approach could reduce drug-related hospital readmissions and improve medication safety for older adults taking multiple medications.

What could go wrong

This is a single trial testing a complex care process, and results may vary across hospitals. The benefit may be modest or not generalizable to all older patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POLYPHARMACY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Amphia ziekenhuis

    Breda, North Brabant, Netherlands

  • Amsterdam UMC - location VUMC

    Amsterdam, North Holland, Netherlands

  • Amsterdam UMC- location AMC

    Amsterdam, North Holland, Netherlands

  • Canisius Wilhelmina Ziekenhuis

    Nijmegen, Gelderland, Netherlands

  • Catharina Ziekenhuis

    Eindhoven, North Brabant, Netherlands

  • Deventer Ziekenhuis

    Deventer, Overijssel, Netherlands

  • Diakonessenhuis

    Utrecht, Utrecht, Netherlands

  • Erasmus Medisch Centrum Rotterdam

    Rotterdam, South Holland, Netherlands

  • Haga Ziekenhuis

    The Hague, South Holland, Netherlands

  • Leiden Universitair Medisch Centrum

    Leiden, South Holland, Netherlands

  • Meander Medisch Centrum Amersfoort

    Amersfoort, Utrecht, Netherlands

  • Radboudumc

    Nijmegen, Gelderland, Netherlands

  • Universitair Medisch Centrum Groningen

    Groningen, Provincie Groningen, Netherlands

  • Universitair Medisch Centrum Utrecht

    Utrecht, Utrecht, Netherlands

  • Zaans Medisch Centrum

    Zaandam, North Holland, Netherlands

  • Ziekenhuisgroep Twente

    Almelo, Overijssel, Netherlands