Could a better medication review keep older adults out of the hospital?

NCT ID NCT05899114

Completed Disease control Sponsor: Radboud University Medical Center Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This trial tests whether a structured medication review and care coordination (TMPC) can reduce drug-related hospital readmissions in adults aged 70 and older who take five or more regular medications. Participants receive a detailed medication analysis, discussions among hospital and community doctors, and a patient interview. The study compares this approach to usual care to see if it lowers readmissions within 30 days and is cost-effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transitional Multidisciplinary Pharmacotherapeutic Care (TMPC) - a structured medication review with care coordination
What this could lead to: If effective, this approach could reduce drug-related hospital readmissions and improve medication safety for older adults taking multiple medications.
What could go wrong: This is a single trial testing a complex care process, and results may vary across hospitals. The benefit may be modest or not generalizable to all older patients.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MEDICATION REVIEW POLYPHARMACY

Contacts and locations

Locations

Amphia ziekenhuis

Breda, North Brabant, Netherlands
Amsterdam UMC - location VUMC

Amsterdam, North Holland, Netherlands
Amsterdam UMC- location AMC

Amsterdam, North Holland, Netherlands
Canisius Wilhelmina Ziekenhuis

Nijmegen, Gelderland, Netherlands
Catharina Ziekenhuis

Eindhoven, North Brabant, Netherlands
Deventer Ziekenhuis

Deventer, Overijssel, Netherlands
Diakonessenhuis

Utrecht, Utrecht, Netherlands
Erasmus Medisch Centrum Rotterdam

Rotterdam, South Holland, Netherlands
Haga Ziekenhuis

The Hague, South Holland, Netherlands
Leiden Universitair Medisch Centrum

Leiden, South Holland, Netherlands
Meander Medisch Centrum Amersfoort

Amersfoort, Utrecht, Netherlands
Radboudumc

Nijmegen, Gelderland, Netherlands
Universitair Medisch Centrum Groningen

Groningen, Provincie Groningen, Netherlands
Universitair Medisch Centrum Utrecht

Utrecht, Utrecht, Netherlands
Zaans Medisch Centrum

Zaandam, North Holland, Netherlands
Ziekenhuisgroep Twente

Almelo, Overijssel, Netherlands

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