PERIPHERAL VASCULAR DISEASES

This study tests whether computer alerts can help doctors prescribe cholesterol-lowering drugs to people with peripheral artery disease (PAD) who aren't taking them. About 400 adults with PAD will be randomly assigned to have their doctors receive an alert or not. The goal is to …

This study is collecting information from 5,000 people with peripheral vascular disease who are being treated with Boston Scientific drug-eluting devices in everyday medical practice. The goal is to see how well these devices work and how safe they are in a wide range of patients…

This study tests whether using carbon dioxide gas instead of standard iodinated contrast dye during leg artery procedures can prevent serious kidney problems. About 1,960 people with peripheral artery disease who are at higher risk for kidney injury will be randomly assigned to r…

This early-phase trial tests whether a single dose of Vumerity (diroximel fumarate) can improve blood vessel function and walking ability in 20 people aged 50-75 with peripheral artery disease (PAD). Participants will receive either Vumerity or a placebo, and researchers will mea…

This pilot study tests whether fisetin, a natural compound found in strawberries, can reduce aging cells and improve walking ability in 34 people aged 50+ with peripheral artery disease (PAD). Participants will receive either fisetin or a placebo for 4 months. The main goal is to…

This study tests whether adding nitrate-rich beetroot juice to exercise helps people with peripheral artery disease (PAD) walk farther and with less pain. 210 adults aged 50+ with PAD will be assigned to either supervised treadmill or home walking, plus either beetroot juice or a…

This study looks at how exercise training impacts blood vessel function in people with PTSD or generalized anxiety disorder, compared to healthy individuals. Researchers want to understand if harmful substances called oxidants play a role in blood vessel damage. The study involve…

This study looks at how different exercise programs affect blood vessel function in people with PTSD or generalized anxiety disorder, compared to healthy individuals. Researchers will measure changes in arm and leg blood vessel dilation after 10 weeks of strength training. The go…

This study uses MRI scans to look at plaque buildup in leg arteries of people with peripheral arterial disease. Researchers want to see which plaques are hard to cross with a guidewire and which devices cause the least damage to the vessel wall. The study includes patients underg…

This study looks at how different exercise programs affect blood vessel function in people with PTSD or generalized anxiety disorder. Researchers will compare moderate versus high intensity exercise in 360 participants. The goal is to see if exercise can improve vascular health, …

This study is collecting information from up to 10,000 people who receive BALT medical devices for conditions like brain aneurysms, stroke, and blocked arteries. Researchers will track how well the devices work and if any safety issues arise during routine care. The goal is to ga…