PERIPHERAL VASCULAR DISEASES

This early-stage study is testing if a single dose of an existing drug, diroximel fumarate (Vumerity), can help people with peripheral artery disease (PAD) walk better. Researchers believe the drug may reduce harmful stress in blood vessels, improving blood flow to the legs. Abou…

This large study is testing whether using automated carbon dioxide injections, instead of standard iodine-based dye, during leg artery procedures can better protect patients' kidneys. It focuses on nearly 2,000 people with poor circulation and a moderate risk of kidney damage fro…

This study is testing whether a computer alert in the medical record system can help doctors prescribe cholesterol-lowering medications to patients with peripheral artery disease (PAD) who are not currently on treatment. The alert reminds both doctors and patients about guideline…

This study is collecting real-world information on how well commercially available, drug-coated devices work for treating blocked arteries in the legs. It will follow 5,000 patients who receive these standard treatments to track outcomes like repeat procedures, amputations, and d…

This study aims to understand how different types of exercise training affect blood vessel function. It will compare healthy individuals with people who have post-traumatic stress disorder (PTSD) or generalized anxiety disorder (GAD). Researchers will measure blood vessel health …

This study aims to understand how exercise training might improve blood vessel function in people with post-traumatic stress disorder (PTSD) or generalized anxiety disorder (GAD). Researchers will test 720 participants, including healthy individuals and those with these mental he…

This study is collecting real-world information about how well medical devices work and how safe they are after they've been approved for treating brain aneurysms, strokes, and other blood vessel problems. It will follow up to 10,000 patients who have already received these devic…

This study aims to understand how different types of weightlifting exercise affect blood vessel function. Researchers will compare healthy adults to those with post-traumatic stress disorder (PTSD) or generalized anxiety disorder (GAD). Participants will complete various tests an…

This study aims to use MRI scans to identify which artery blockages in the legs are most difficult to treat with standard procedures. Researchers will scan patients before their artery-opening procedures and test different medical devices on donated limbs to see which cause less …