PERIPHERAL VASCULAR DISEASES

This study tests whether fisetin, a natural compound, can reduce aging cells in the body and improve walking ability in 34 people aged 50+ with peripheral artery disease (PAD). Participants will take fisetin or a placebo for 4 months. The main goal is to see if fisetin helps them…

This study tests whether adding nitrate-rich beetroot juice to exercise (either supervised treadmill sessions or home walking) improves walking distance more than exercise alone in people with peripheral artery disease (PAD). About 210 adults aged 50 and older with PAD will be ra…

This study tests a new way to perform leg artery procedures that may protect the kidneys. Instead of using standard contrast dye, doctors will use carbon dioxide gas to see the arteries. The goal is to prevent serious kidney problems in the 90 days after the procedure. About 1,96…

This study tests whether a single dose of the drug Vumerity can improve blood vessel function and walking ability in people with peripheral artery disease (PAD). Researchers will give 20 adults aged 50-75 either Vumerity or a placebo and measure changes in blood flow, oxygen use,…

This study tests whether a computer alert system can help doctors remember to prescribe cholesterol-lowering medications to people with peripheral artery disease (PAD) who aren't currently taking them. About 400 adults with PAD will take part. The goal is to see if the alerts lea…

This study looks at how different types of exercise affect blood vessel function in healthy people and those with PTSD or generalized anxiety disorder. Researchers will measure changes in blood flow and artery dilation. The goal is to understand if exercise can help improve vascu…

This study looks at how exercise training impacts blood vessel function in people with PTSD or generalized anxiety disorder. Researchers want to understand if harmful substances in the blood (oxidants) play a role. The study involves 720 adults who are otherwise healthy and will …

This study looks at people with severe peripheral artery disease (blocked leg arteries). Researchers will use MRI scans before treatment to see which blockages are hard to cross and which tools cause the least damage to blood vessels. The goal is to learn how to make procedures s…

This study looks at how different types of exercise affect blood vessel function in healthy people and those with PTSD or generalized anxiety disorder. Researchers will measure changes in blood flow and artery dilation. The goal is to understand if exercise can help improve vascu…

This study is not testing a new treatment but gathering information on how well BALT medical devices work in real-world use for conditions like brain aneurysms, stroke, and vascular diseases. Up to 10,000 participants will be followed to track device safety, performance, and ease…

This study is a large registry that will collect information from 5,000 people with peripheral vascular disease who are treated with Boston Scientific drug-eluting devices in everyday medical practice. The goal is to gather real-world data on safety and effectiveness, including i…