PEDIATRIC OBESITY

This study compares two weight management programs for children who have had acute lymphoblastic leukemia (ALL). About 80 children and their caregivers will be randomly assigned to either a basic educational program or a more intensive guided self-help program. The goal is to see…

This study looks at whether adding lifestyle coaching to a new weight-loss medication (GLP-1) helps teens with obesity lose more weight and feel better. About 1,020 teens aged 12-17 will take the medication and be assigned to either intensive or basic lifestyle support. The goal …

This study looks at whether day hospitalization (going home at night) works as well as full-time hospital stays for teens aged 12-20 with severe obesity. About 126 participants will be followed to see how their weight changes six months after treatment ends. The goal is to find a…

This study tests a telehealth program called Virtual Housecalls for teens aged 12-15 with class I obesity. The program provides 26 hours of lifestyle coaching via video calls. Researchers want to see if it helps teens maintain a healthier weight compared to standard care. The tri…

This study tests whether restarting semaglutide (Wegovy) just two weeks after sleeve gastrectomy helps teens with severe obesity lose more weight than surgery alone. About 150 teens aged 12–18 who were already on semaglutide before surgery will be randomly assigned to restart the…

This study tests whether a combination of blood markers, ultrasound, and genetic information can accurately diagnose metabolic dysfunction-associated steatotic liver disease (MASLD) in children aged 8 to 18 with obesity. Each child provides a blood sample, undergoes a liver ultra…

This study tests whether a trauma therapy program can help children aged 10 to 17 who have been bullied because of their weight. The therapy is based on Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and aims to reduce emotional distress, improve body image, and address eat…

This study explores whether polycystic ovary syndrome (PCOS) independently contributes to fatty liver disease in adolescent girls, beyond the effects of obesity. Researchers will compare three groups of girls aged 10–18: those with PCOS and obesity, those with obesity alone, and …

This study will use a painless ultrasound to examine tongue stiffness, thickness, and other features in 80 adolescents aged 12-18 with obesity and sleep-disordered breathing. Participants are already enrolled in a weight-loss program. The goal is to better understand how the tong…