PEDIATRIC OBESITY

This study tests a combination of two weight-loss drugs (phentermine and topiramate) in 13 teenagers aged 12-20 who have both obesity and type 2 diabetes. The goal is to see if the medication can safely lower body mass index (BMI) over 6 months. The drugs are already approved for…

This study looks at whether a protein supplement called carnitine can help reduce hardening of the arteries in teenagers at high risk for future heart disease. About 90 teens aged 11-21 with high triglycerides will take carnitine or a placebo. The goal is to see if carnitine can …

This study compares weight-loss surgery to intensive medical treatment for controlling type 2 diabetes in teenagers aged 13 to 19.9 years. The goal is to see if surgery is better at keeping blood sugar levels healthy and reducing related health problems. Participants are randomly…

This study tests whether a parent-only program followed by a parent-child program works better for weight loss than the parent-child program alone. It involves 480 rural families with children aged 6-11 who are overweight. Families participate via video calls, and researchers tra…

This study tests a program called TrailGuide that helps doctors connect children with obesity to local parks and recreation activities. About 400 children aged 5-12 with a high BMI will take part. The goal is to see if this approach improves their weight, physical activity, and q…

This study tests whether a family-focused lifestyle program can lower type 2 diabetes risk and improve quality of life in high-risk Latino families. About 132 Latino children aged 10-16 with obesity take part. The program focuses on healthy eating and physical activity to prevent…

This study tests a 12-week program that teaches parents how to encourage healthy eating in their children aged 5 to 11 who are at risk for obesity. The program focuses on setting routines and letting kids make good food choices. Researchers will check if parents stick with the pr…