PEDIATRIC CANCER

This study tests two immunotherapy drugs, durvalumab and tremelimumab, in children aged up to 17 with advanced solid tumors or certain blood cancers that have not responded to standard treatments. The first part finds the safest dose, and the second part checks if the drugs can s…

This study looks at children born with birth defects who later develop cancer, aiming to find shared genetic causes. Researchers will analyze DNA from 1,000 children and their parents. The goal is to improve cancer risk monitoring and care for children with birth defects.

This study is testing a mobile app called ATOMIC designed to help children, teens, and young adults who survived childhood cancer become more physically active. About 35 survivors aged 10 to 30 who received a specific type of chemotherapy will try the app. Researchers will see ho…

This study creates a large registry to collect information from nearly 58,000 children diagnosed with cancer or similar conditions in the U.S. and Canada. The goal is to help researchers study patterns, causes, and characteristics of childhood cancers. Parents provide details abo…

This study gathers imaging data from 367 children receiving proton therapy for cancer. Researchers use daily scans to measure how precisely patients are positioned, compare 2D and 3D imaging methods, and identify factors that cause large positioning errors. The goal is to make fu…

This study tests a digital tool that lets children and teens with cancer, along with their caregivers, report symptoms to their doctors during clinic visits. The goal is to see if the tool is easy to use and helpful for both families and doctors. The study includes 83 participant…

This study looks at how to best screen families of children newly diagnosed with cancer for emotional, social, and practical needs. Researchers are comparing two ways to roll out a screening tool called the Psychosocial Assessment Tool (PAT) across 18 U.S. cancer centers. The goa…

This study looks at why some children with cancer don't get the physical or occupational therapy they need. Researchers will interview doctors, therapists, and hospital administrators to find out what helps or hinders access. The goal is to reduce unfair differences in care and i…

This study looks at how surviving a pediatric brain tumor affects children's thinking, memory, and behavior. Researchers will track how many eligible survivors join the study to see if this type of research is possible. The goal is to better understand the long-term effects of ca…

This study looks at whether an iPad-based thinking exercise program is practical for children and teens who had a stem cell transplant for leukemia. Researchers want to see if kids can stick with the program and if it helps their memory and problem-solving skills. Only 17 partici…