ORAL LICHEN PLANUS
Clinical trials for ORAL LICHEN PLANUS explained in plain language.
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Ancient neem tree tested against modern medicine for mouth condition
Disease control CompletedThis study tested whether a gel made from the natural neem plant works as well as a standard steroid medication for treating oral lichen planus, a chronic inflammatory mouth condition. Sixty adults with the condition applied either neem gel or the steroid paste twice daily for th…
Matched conditions: ORAL LICHEN PLANUS
Phase: PHASE1, PHASE2 • Sponsor: Goa Dental College • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope for painful mouth sores: study tests safer treatment options
Disease control CompletedThis study compared two add-on medications, apremilast and methotrexate, for treating moderate to severe oral lichen planus when used alongside standard steroid therapy. It involved 64 adults who hadn't responded well to steroid creams or injections alone. The main goal was to se…
Matched conditions: ORAL LICHEN PLANUS
Phase: PHASE4 • Sponsor: All India Institute of Medical Sciences, Bhubaneswar • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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Gentler biopsy? laser shows promise for oral tissue sampling
Diagnosis CompletedThis study compared two methods for taking a small tissue sample (biopsy) from the mouth to diagnose oral lichen planus. Researchers tested whether using a laser caused less discomfort and healed as well as the standard punch tool. Over 100 adults with the condition had one of th…
Matched conditions: ORAL LICHEN PLANUS
Phase: NA • Sponsor: Catholic University of the Sacred Heart • Aim: Diagnosis
Last updated Mar 30, 2026 14:33 UTC
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Spit test could help spot mouth diseases
Knowledge-focused CompletedThis study aimed to find out if the proteins in saliva differ between people with two specific mouth conditions and healthy individuals. Researchers collected saliva samples from 21 people with oral lichen planus, oral leukoplakia, or no mouth disease. By analyzing the protein pa…
Matched conditions: ORAL LICHEN PLANUS
Sponsor: Kocaeli University • Aim: Knowledge-focused
Last updated Apr 02, 2026 01:11 UTC
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Scientists investigate hidden link between mouth sores and thyroid problems
Knowledge-focused CompletedThis study aimed to understand the connection between oral lichen planus, a chronic inflammatory mouth condition, and autoimmune thyroid diseases like Hashimoto's thyroiditis. Researchers enrolled 150 participants to see how often these conditions occur together and if the severi…
Matched conditions: ORAL LICHEN PLANUS
Sponsor: The Dental Hospital of Zhejiang University School of Medicine • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC