ORAL LICHEN PLANUS
Clinical trials for ORAL LICHEN PLANUS explained in plain language.
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New drug may offer safer relief for painful mouth condition
Disease control CompletedThis study tested two drugs, apremilast and methotrexate, added to standard steroid treatment for oral lichen planus, a chronic inflammatory mouth condition causing pain and sores. 64 adults with moderate to severe disease who didn't respond to topical steroids took either apremi…
Matched conditions: ORAL LICHEN PLANUS
Phase: PHASE4 • Sponsor: All India Institute of Medical Sciences, Bhubaneswar • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Neem vs. steroid: can a natural gel tame oral lichen planus?
Disease control CompletedThis study tested whether a neem gel can treat oral lichen planus, a chronic inflammatory mouth condition, as well as a standard steroid paste. Sixty adults used either neem or triamcinolone acetonide twice daily for three months. Researchers measured pain, lesion severity, and a…
Matched conditions: ORAL LICHEN PLANUS
Phase: PHASE1, PHASE2 • Sponsor: Goa Dental College • Aim: Disease control
Last updated Jun 26, 2026 13:01 UTC
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Light therapy vs. steroids: which saves your taste buds?
Symptom relief CompletedThis study looked at two treatments for oral lichen planus, a chronic mouth condition that can cause pain and change how food tastes. Researchers compared a light-based treatment (photodynamic therapy) with steroid cream in 65 adults. They measured taste ability, pain, and lesion…
Matched conditions: ORAL LICHEN PLANUS
Phase: NA • Sponsor: Medical University of Bialystok • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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New light device eases mouth pain in lichen planus
Symptom relief CompletedThis study tested a home-use light device and special mouth rinse to help people with oral lichen planus, a painful mouth condition. Thirteen participants used the device daily for a year alongside standard care. The goal was to see if it could reduce pain and inflammation better…
Matched conditions: ORAL LICHEN PLANUS
Phase: NA • Sponsor: Koite Health Oy • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Could a seed protein stop oral cancer? early study hints at promise
Knowledge-focused CompletedThis early-phase study looked at whether a protein from the Maackia amurensis seed (MASL) can target a receptor called podoplanin found on oral cancer and precancerous cells. Researchers measured how much of this receptor was present in tissue samples from 18 adults with suspicio…
Matched conditions: ORAL LICHEN PLANUS
Phase: EARLY_PHASE1 • Sponsor: Rowan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Laser vs scalpel: which biopsy hurts less for mouth disease?
Knowledge-focused CompletedThis study tested whether using a laser for oral biopsies causes less pain and heals better than the standard punch scalpel in people with oral lichen planus. 112 adults were randomly assigned to one of the two methods. Researchers measured wound healing and discomfort after the …
Matched conditions: ORAL LICHEN PLANUS
Phase: NA • Sponsor: Catholic University of the Sacred Heart • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Saliva secrets: could proteins tell two mouth diseases apart?
Knowledge-focused CompletedThis study looked at saliva from 21 people: some with oral lichen planus, some with oral leukoplakia, and some healthy. The goal was to see if proteins in saliva are different between these groups. Researchers hope these protein differences could one day help doctors tell these t…
Matched conditions: ORAL LICHEN PLANUS
Sponsor: Kocaeli University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Mouth condition may signal thyroid trouble
Knowledge-focused CompletedThis study examined 150 people with oral lichen planus (OLP) to see if there is a link with autoimmune thyroid diseases. Researchers measured thyroid function and antibodies in participants' blood. The goal was to find patterns that could help predict or manage these conditions t…
Matched conditions: ORAL LICHEN PLANUS
Sponsor: The Dental Hospital of Zhejiang University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC