Neem vs. steroid: can a natural gel tame oral lichen planus?
NCT ID NCT07141446
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether a neem gel can treat oral lichen planus, a chronic inflammatory mouth condition, as well as a standard steroid paste. Sixty adults used either neem or triamcinolone acetonide twice daily for three months. Researchers measured pain, lesion severity, and anxiety to see if neem is a viable alternative.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Neem gel (1.5%) and triamcinolone acetonide (0.1%)
What this could lead to
If neem works as well as the steroid, it could offer a natural, safer option for managing oral lichen planus symptoms.
What could go wrong
This is a small, early-phase trial with only 60 participants. Neem may not be as effective as the standard treatment, and results may not apply to everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Oral Medicine and radiology, Goa Dental College and Hospital, Bambolim Goa India
Goā, Bambolim, 403202, India