Neem vs. steroid: can a natural gel tame oral lichen planus?

NCT ID NCT07141446

Completed Disease control Sponsor: Goa Dental College Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a neem gel can treat oral lichen planus, a chronic inflammatory mouth condition, as well as a standard steroid paste. Sixty adults used either neem or triamcinolone acetonide twice daily for three months. Researchers measured pain, lesion severity, and anxiety to see if neem is a viable alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Neem gel (1.5%) and triamcinolone acetonide (0.1%)
What this could lead to: If neem works as well as the steroid, it could offer a natural, safer option for managing oral lichen planus symptoms.
What could go wrong: This is a small, early-phase trial with only 60 participants. Neem may not be as effective as the standard treatment, and results may not apply to everyone.

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Conditions

The condition(s) this trial relates to.

lichen planus, oral

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL LICHEN PLANUS

Contacts and locations

Locations

Department of Oral Medicine and radiology, Goa Dental College and Hospital, Bambolim Goa India

Goā, Bambolim, 403202, India

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