OPTIC NEURITIS

This study tests whether starting plasma exchange early, rather than waiting, leads to better vision in severe optic neuritis and less disability in severe transverse myelitis. About 382 adults with these inflammatory nerve conditions will be randomly assigned to early or rescue …

This study tests whether clemastine fumarate, a drug originally approved for allergies, can help repair nerve damage in people with acute optic neuritis (inflammation of the optic nerve). About 90 participants will receive either clemastine or a placebo for 9 months. Researchers …

This study tests a new drug called privosegtor in 210 adults with a first episode of optic neuritis, a condition that causes sudden vision loss. Participants receive either privosegtor or a placebo, both alongside standard steroid treatment. The goal is to see if the drug helps r…

This study looks at how well new international guidelines can diagnose optic neuritis, a condition where the eye's nerve gets inflamed and causes sudden vision loss. Researchers in China will study 500 people with sudden vision loss to see if the guidelines correctly identify opt…

This study tests an experimental drug, efgartigimod alfa, against a placebo in 20 adults experiencing their first episode of optic neuritis (inflammation of the nerve connecting the eye to the brain). The goal is to see if the drug can help vision return faster and more fully, on…