OLIGOPROGRESSIVE METASTATIC DISEASE
Clinical trials for OLIGOPROGRESSIVE METASTATIC DISEASE explained in plain language.
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Can zapping just the growing spots keep cancer in check?
Disease control Recruiting nowThis study is for people with stage IV cancer that has started to grow in only a few places (oligoprogression). It compares adding local treatments like radiation or surgery to all growing spots versus switching to a new systemic therapy. The goal is to see if this approach can b…
Matched conditions: OLIGOPROGRESSIVE METASTATIC DISEASE
Phase: PHASE2, PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Radiation zaps may buy time for melanoma patients
Disease control Recruiting nowThis study is for people with metastatic melanoma whose cancer has started growing in a few spots despite treatment. Researchers want to see if giving high-dose, precise radiation to those spots can delay further spread. About 52 adults will take part, and the main goal is to see…
Matched conditions: OLIGOPROGRESSIVE METASTATIC DISEASE
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Zapping resistant tumors: could radiation keep breast cancer therapy working longer?
Disease control Recruiting nowThis phase 2 trial tests whether giving precise radiation (SBRT) to a few growing cancer spots can help women with ER+/HER2- metastatic breast cancer stay on their current hormone therapy or CDK4/6 inhibitor longer. The study enrolls 48 women whose cancer has started to progress …
Matched conditions: OLIGOPROGRESSIVE METASTATIC DISEASE
Phase: NA • Sponsor: Jules Bordet Institute • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Precision radiation may buy more time for patients with spreading cancer
Disease control Recruiting nowThis study tests whether a precise, high-dose radiation technique called SABR works better than standard palliative radiation for people whose cancer has spread to a few new spots while on treatment. About 194 adults with solid tumors (excluding lymphoma or myeloma) and up to 5 g…
Matched conditions: OLIGOPROGRESSIVE METASTATIC DISEASE
Phase: NA • Sponsor: British Columbia Cancer Agency • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Triple attack on kidney cancer: immune booster, radiation, and immunotherapy
Disease control Recruiting nowThis study tests whether adding an immune-boosting drug (IMSA101) and targeted radiation to standard immunotherapy can help control metastatic kidney cancer that has started to grow again. About 15 adults with clear cell kidney cancer that has progressed in up to 5 spots will rec…
Matched conditions: OLIGOPROGRESSIVE METASTATIC DISEASE
Phase: PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Zapping cancer spots: could radiation delay the need for stronger drugs?
Disease control Recruiting nowThis phase 2 trial tests whether giving focused radiation (SBRT) to a few growing prostate cancer spots, while staying on current therapy, can control the cancer better than switching to a new systemic therapy. About 75 men with castration-resistant prostate cancer that has a lim…
Matched conditions: OLIGOPROGRESSIVE METASTATIC DISEASE
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 26, 2026 13:35 UTC