OBESITY TYPE 2 DIABETES MELLITUS

This trial tests a new laparoscopic procedure called SIBS, which combines sleeve gastrectomy with a side-to-side connection between the duodenum and ileum, without cutting the duodenum. The goal is to see if the surgery is safe and technically feasible in adults with obesity and …

This study tests whether adding fecal microbiota transplantation (FMT) to a calorie-restricted diet and a diabetes drug (semaglutide) helps people with obesity and type 2 diabetes lose more weight and improve metabolism. Twenty adults aged 18-60 with a BMI of 30-40 and diabetes f…

This study tests a temporary device placed in the upper small intestine to help control type 2 diabetes and obesity. The implant stays for 6 months and is then removed. Researchers will check if it lowers blood sugar (HbA1c), helps with weight loss, and improves liver health in p…

This study looks at whether levels of a protein called Neuregulin-4 (NRG4) in the blood are linked to obesity, insulin resistance, and different diabetes treatments in people with type 2 diabetes. Researchers will compare NRG4 levels across groups including obese and non-obese pa…

This study looks at whether certain autoantibodies (proteins that mistakenly attack the body) are more common in people with obesity and if they are linked to related health problems like type 2 diabetes. Researchers will study 160 adults with a BMI over 30. The goal is to better…

This registry study will follow 10,000 Chinese adults with obesity or overweight across 50 hospitals. Researchers will collect data on weight, lab tests, and liver health over 6 and 12 months. The goal is to understand current treatment patterns and outcomes in real-world clinica…

This study will screen up to 10,000 adults aged 18-75 who are overweight or have metabolic issues like high blood sugar or cholesterol. Researchers will use questionnaires, blood tests, and liver ultrasounds to find out how common fatty liver disease is and what factors increase …