OBESITY, CHILDHOOD

This study tests whether combining lifestyle counseling with weight-loss medication helps teens aged 12–17 with severe obesity lose weight. About 120 participants will receive counseling and medication for a year. The goal is to find a practical, effective treatment that is easie…

This study tests a family-based program called LEADS for overweight African American teens and their parents. The program teaches stress-coping skills, mindfulness, and positive parenting to help teens become more physically active. Researchers will measure changes in daily exerc…

This study tests a 6-month home-based program called FIT Families, designed to help African American teens with obesity and their caregivers lose weight. The program includes coaching sessions, family counseling, and small prizes for completing tasks. Researchers will measure cha…

This study tests a telehealth program that teaches parents of children with autism and overweight or obesity how to help their child manage weight through nutrition, activity, and behavior skills. About 140 families will take part, with one group receiving the parent-based progra…

This study tests a program that teaches parents how to help their child, a childhood cancer survivor, eat healthy and exercise more. The goal is to prevent or reduce obesity, which is a major risk for heart disease in these children. About 520 families will take part in one of tw…

This study tests a 10-week program called Healthy Dads, Healthy Kids for Hispanic families in Houston. Dads aim to lose weight, while kids increase physical activity through group sessions and joint exercise. About 187 fathers and their children are taking part to see if the prog…

This study tests whether semaglutide (Wegovy), a once-weekly injection, can preserve the pancreas's ability to produce insulin and reduce liver fat in 60 obese youth with prediabetes or early type 2 diabetes and fatty liver disease. Participants receive either semaglutide or a pl…

This study tests whether limiting food intake to an 8-hour window each day (between 10am and 6pm) for 2 months helps children and teens with obesity lose weight. Researchers will also check if any benefits last and explore how the gut microbiome and body clock might play a role. …

This study tests a postbiotic supplement called ABB C3 in 70 children and teens with obesity. Half take the supplement and half take a placebo for 3 months, with an optional 3-month extension for all. Researchers will measure changes in body fat and blood sugar levels to see if t…

This study was designed to treat toddler obesity by improving the food environment at home. Parents would take part in a free online nutrition program and could also take weight-loss medication. The goal was to help both parent and child lose weight. However, the study was withdr…

This study tests a program called WISE Words that helps childcare educators stop using feeding practices that can lead to obesity in young children. The program includes training, peer support, and personalized reminders. Researchers will observe mealtimes at over 260 childcare s…

This study looks at whether a program that helps mothers and caregivers feed their babies in a more responsive way can prevent childhood obesity. About 165 mothers and their 4-5 month old babies will take part. The program focuses on improving diet quality and feeding behaviors t…

This study looks at how to best help childcare centers use proven methods to improve kids' diets, like hands-on activities with fruits and vegetables. About 1,850 teachers and staff from Arkansas and Louisiana will take part. The goal is to see if giving extra support to centers …

This study tests a family program called Turtle Island Tales to help prevent obesity and cancer in American Indian communities. About 200 caregivers with children ages 3 to 8 living in low-income areas will take part. The program focuses on healthy eating, physical activity, less…

This study looks at how changing sleep patterns affects eating behavior and self-control in 120 children who are overweight or at risk for obesity. Researchers will monitor sleep, brain activity, and real-world eating to understand the link between sleep and weight gain. The goal…

This study looks at how a baby's emotions, attachment to mom, and feeding habits work together to affect weight gain in the first year of life. Researchers will follow 250 mother-infant pairs to understand what leads to healthy growth or future obesity. The goal is to find ways t…

This study looks at the genes of 1000 people with severe early-onset obesity to find rare genetic causes. It focuses on conditions like Bardet-Biedl syndrome. The goal is to better understand these conditions and improve how they are diagnosed. Participants provide a blood or sal…