NEOPLASMS

This early-stage trial is testing a new drug called LRK-4189 to see if it is safe and might help treat advanced solid tumors, especially colorectal cancer. About 120 adults whose cancer has worsened despite treatment will take the drug alone or combined with standard chemotherapy…

This study follows young girls (ages 0-18) with cancer who have frozen a piece of their ovarian tissue before treatment. The goal is to see if transplanting this tissue back later is safe and can lead to successful pregnancies. Researchers will track surgical complications and pr…

This is the first study in people for a new cancer drug called GSK5533524. It aims to find a safe dose and see how well adults with advanced solid tumors that have stopped responding to standard treatments can tolerate it. Researchers will also check if the drug can shrink tumors…

This study is testing a new imaging agent for PET/CT scans to see if it can better detect and locate cancer. The agent is designed to stick to cancer cells, making them easier to see on a scan. About 98 adults with confirmed or suspected cancer will get one injection and one scan…

This study is testing a 4-week online self-help program designed to support the mental and emotional well-being of people who have recently finished curative cancer treatment. It will see if the program is easy to use and acceptable, and if it shows early signs of improving feeli…

This observational study aims to understand how immunotherapy affects physical fitness and quality of life in adults with advanced solid cancers. Researchers will measure fitness and quality of life before and during standard immunotherapy treatment to see if a patient's fitness …

This research aims to understand how travel distance affects cancer patients' access to treatment. By analyzing where 300 patients treated since 2020 live relative to Delafontaine Hospital, researchers will map travel times and transportation challenges. The goal is to identify i…