NAFLD

This study tests whether semaglutide (a once-daily pill) works better than sitagliptin (another diabetes drug) at controlling blood sugar and body weight in people who have had a liver transplant and have poorly controlled diabetes. About 58 adults who are at least 3 months post-…

This study looks at how a temporary stomach balloon affects weight, liver health, and quality of life in 200 people with nonalcoholic fatty liver disease (NAFLD) and obesity. Participants will be followed for at least one year after the balloon is placed. The goal is to see if th…

This study tests whether empagliflozin, a diabetes drug, can prevent liver scarring (fibrosis) from getting worse in people with chronic hepatitis B. About 106 adults with moderate to severe liver scarring will take either the drug or a placebo daily for three years. The goal is …

This study tests an experimental drug called efinopegdutide in 80 adults with liver cirrhosis caused by metabolic dysfunction-associated steatohepatitis (MASH), a type of fatty liver disease. The goal is to see if the drug can lower liver fat, inflammation, and scarring compared …

This study tests whether a very low-calorie diet (800-960 calories per day) can reduce liver fat and scarring in 20 adults with obesity and non-alcoholic fatty liver disease (NAFLD). Participants follow the diet for 8 weeks, and researchers measure liver changes using a special u…

This study was designed to see if a new device that uses sound waves (thermo-acoustic imaging) can accurately measure fat in the liver. It planned to compare the device's results with standard MRI scans in adults with or suspected of having non-alcoholic fatty liver disease. The …

This study tests a new portable device called LiverScope that uses simplified MRI technology to measure fat in the liver. Researchers will compare it to standard MRI and ultrasound exams in 50 adults with known or suspected fatty liver disease. The goal is to see if this small, t…

This study checks if new MRI and ultrasound techniques can accurately measure liver fat in children ages 10-14, both those with obesity and those at a healthy weight. The goal is to see if these painless imaging methods work well for diagnosing fatty liver disease (NAFLD) without…

This study follows 400 adults with HIV to learn how nonalcoholic fatty liver disease (NAFLD) develops and progresses in this group. Researchers use a non-invasive ultrasound-like scan to measure liver fat and stiffness over one year. The goal is to fill major knowledge gaps, sinc…

This study looks at how often fatty liver disease occurs in people living with HIV. Researchers will use a special ultrasound scan to measure liver fat in 1,250 adults with HIV who are on stable treatment. The goal is to better understand this liver condition in people with HIV, …

This study aims to find out how many people with type 2 diabetes also have non-alcoholic fatty liver disease (NAFLD). Researchers will use a special ultrasound scan (FibroScan) to check the liver health of 385 adults with type 2 diabetes. The goal is to better understand how ofte…