HIV and fatty liver: a hidden danger under the microscope

NCT ID NCT05023044

Ongoing Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 400 adults with HIV to learn how nonalcoholic fatty liver disease (NAFLD) develops and progresses in this group. Researchers will use a non-invasive scan to measure liver stiffness and fat content over one year. The goal is to fill major knowledge gaps, since previous studies excluded people with HIV.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal how NAFLD progresses in people with HIV, guiding future treatments and monitoring strategies.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly improve health. Results may take years and might not apply to all HIV patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV NAFLD NASH - NONALCOHOLIC STEATOHEPATITIS

Contacts and locations

Locations

Duke University

Durham, North Carolina, 27710, United States
Indiana University

Indianapolis, Indiana, 46202, United States
Johns Hopkins University

Baltimore, Maryland, 21287, United States
University of Alabama

Birmingham, Alabama, 35233, United States
University of California, San Diego

San Diego, California, 92121, United States
University of California, San Francisco

San Francisco, California, 94143, United States
University of Texas

Houston, Texas, 77030, United States
Virginia Commonwealth University

Richmond, Virginia, 23284, United States

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