Can a popular diabetes drug help liver transplant patients control blood sugar?

NCT ID NCT05195944

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two diabetes medications, semaglutide and sitagliptin, in 58 adults who have had a liver transplant and have poorly controlled diabetes. The goal is to see which drug better lowers blood sugar and body weight. Participants will take the study drug daily for the trial duration, and all will continue standard post-transplant medications for life.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Toronto General Hospital

    Toronto, Ontario, M5G 2N2, Canada