MUSCLE-INVASIVE BLADDER CANCER
Clinical trials for MUSCLE-INVASIVE BLADDER CANCER explained in plain language.
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New combo aims to shrink bladder tumors without chemo
Disease control Not yet recruitingThis phase 2 trial tests whether giving focused radiation (SBRT) along with immunotherapy drugs (cemiplimab, with or without fianlimab) before bladder removal can safely shrink muscle-invasive bladder tumors. The study enrolls 44 patients who cannot or choose not to take standard…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Bladder cancer surgery: do stents help or hurt?
Disease control Not yet recruitingThis study looks at whether using ureteral stents (small tubes) after bladder cancer surgery leads to more or fewer problems than not using them. About 190 adults having their bladder removed will be randomly assigned to get stents or not. The main goal is to see who ends up back…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE3 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New hope for bladder cancer: targeted drug combo aims to boost survival
Disease control Not yet recruitingThis study tests whether a combination of disitamab vedotin (a targeted drug) and toripalimab (an immunotherapy) works better than standard chemotherapy plus immunotherapy for people with HER2-positive muscle-invasive bladder cancer. About 240 participants will receive treatment …
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2, PHASE3 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New combo therapy aims to boost bladder cancer treatment before surgery
Disease control Not yet recruitingThis study tests whether adding immunotherapy (toripalimab) to standard chemotherapy before surgery can improve outcomes for people with muscle-invasive bladder cancer. About 30 participants will receive the combination therapy, and researchers will monitor how the tumor and immu…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Bladder cancer showdown: can radiation and chemotherapy match surgery?
Disease control Not yet recruitingThis study compares two treatments for muscle-invasive bladder cancer: radiation combined with chemotherapy versus surgery to remove the bladder. About 336 adults with this cancer will be randomly assigned to one of the two groups. The goal is to see if the non-surgical approach …
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: NA • Sponsor: Brazilian Clinical Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Bladder cancer: can faster chemo before surgery boost cure rates?
Disease control Not yet recruitingThis phase 2 trial tests a dose-dense (faster) schedule of two chemotherapy drugs, gemcitabine and cisplatin, given before surgery for muscle-invasive bladder cancer. The goal is to see if this approach can completely eliminate the tumor in the bladder and lymph nodes. Thirty eli…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2 • Sponsor: Assiut University • Aim: Disease control
Last updated Jun 26, 2026 19:10 UTC
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Can chemo before surgery beat bladder cancer? new study digs into the data.
Knowledge-focused Not yet recruitingThis study reviews medical records of 87 adults with muscle-invasive bladder cancer who received platinum-based chemotherapy before surgery. Researchers want to see what factors influence how well the chemo works and whether it helps patients live longer without cancer. The goal …
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Sponsor: Sara Mahmoud Ahmed Mahmoud • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC