MUSCLE-INVASIVE BLADDER CANCER
Clinical trials for MUSCLE-INVASIVE BLADDER CANCER explained in plain language.
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Bladder cancer: a new combo aims to avoid radical surgery
⭐️ CURE ⭐️ Not yet recruitingThis trial tests whether combining two drugs—disitamab vedotin and toripalimab—with or without pelvic lymph node removal can help people with muscle-invasive bladder cancer keep their bladder. Participants, who have HER2-positive tumors and decline bladder removal surgery, will r…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2, PHASE3 • Sponsor: Tianjin Medical University Second Hospital • Aim: ⭐️ CURE ⭐️
Last updated Aug 12, 2026 00:00 UTC
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Lab-Grown tumor clusters guide tailored bladder cancer therapy
Disease control Not yet recruitingThis study tests a personalized approach for people with muscle-invasive bladder cancer who are scheduled for bladder removal surgery. Before treatment, a small sample of the tumor is used to grow cell clusters in the lab. These clusters are tested against different drugs to find…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2 • Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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New combo aims to shrink bladder tumors without chemo
Disease control Not yet recruitingThis phase 2 trial tests whether giving focused radiation (SBRT) along with immunotherapy drugs (cemiplimab, with or without fianlimab) before bladder removal can safely shrink muscle-invasive bladder tumors. The study enrolls 44 patients who cannot or choose not to take standard…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New hope for bladder cancer: targeted drug combo aims to boost survival
Disease control Not yet recruitingThis study tests whether a combination of disitamab vedotin (a targeted drug) and toripalimab (an immunotherapy) works better than standard chemotherapy plus immunotherapy for people with HER2-positive muscle-invasive bladder cancer. About 240 participants will receive treatment …
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2, PHASE3 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New combo therapy aims to boost bladder cancer treatment before surgery
Disease control Not yet recruitingThis study tests whether adding immunotherapy (toripalimab) to standard chemotherapy before surgery can improve outcomes for people with muscle-invasive bladder cancer. About 30 participants will receive the combination therapy, and researchers will monitor how the tumor and immu…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Bladder cancer showdown: can radiation and chemotherapy match surgery?
Disease control Not yet recruitingThis study compares two treatments for muscle-invasive bladder cancer: radiation combined with chemotherapy versus surgery to remove the bladder. About 336 adults with this cancer will be randomly assigned to one of the two groups. The goal is to see if the non-surgical approach …
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: NA • Sponsor: Brazilian Clinical Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Bladder cancer: can faster chemo before surgery boost cure rates?
Disease control Not yet recruitingThis phase 2 trial tests a dose-dense (faster) schedule of two chemotherapy drugs, gemcitabine and cisplatin, given before surgery for muscle-invasive bladder cancer. The goal is to see if this approach can completely eliminate the tumor in the bladder and lymph nodes. Thirty eli…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Phase: PHASE2 • Sponsor: Assiut University • Aim: Disease control
Last updated Jun 26, 2026 19:10 UTC
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Bladder cancer surgery: what happens after the bladder is removed?
Knowledge-focused Not yet recruitingThis study looks at the well-being and medical care of people in Korea who had their bladder removed (radical cystectomy) for bladder cancer. Using nationwide insurance records, researchers will track complications, hospital stays, readmissions, and survival up to three years aft…
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Sponsor: Janssen Korea, Ltd., Korea • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Can chemo before surgery beat bladder cancer? new study digs into the data.
Knowledge-focused Not yet recruitingThis study reviews medical records of 87 adults with muscle-invasive bladder cancer who received platinum-based chemotherapy before surgery. Researchers want to see what factors influence how well the chemo works and whether it helps patients live longer without cancer. The goal …
Matched conditions: MUSCLE-INVASIVE BLADDER CANCER
Sponsor: Sara Mahmoud Ahmed Mahmoud • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC