MORBID OBESITY

This study tests a new tool called the SFM Anastomosis Device, used during weight loss surgery to connect parts of the intestine. It includes 28 adults with severe obesity (BMI 35-55) who are either having a first-time sleeve gastrectomy with an added intestinal bypass, or have h…

This study planned to test a procedure called bariatric embolization for people with severe obesity who cannot have weight-loss surgery. The procedure would block blood flow to part of the stomach to reduce appetite. However, the study was withdrawn before enrolling any participa…

This study looks at whether a very-low-calorie ketogenic diet (VLCKD) helps people with severe obesity and metabolic syndrome lose more weight and improve heart health over three years compared to a standard Mediterranean diet. About 100 adults aged 55-75 will be randomly assigne…

This study looks at whether two types of exercise training can improve body composition, heart and lung function, and quality of life in people who have had bariatric surgery. Researchers will compare high-intensity interval training (HIIT) and moderate-intensity continuous train…

This study tests whether a combination of ketamine and dexmedetomidine (ketodex) can reduce the need for strong painkillers after laparoscopic sleeve gastrectomy in obese patients. Eight adults with a BMI over 35 are randomly assigned to receive either ketodex or standard opioid-…

This study compares two types of weight-loss surgery—sleeve gastrectomy alone versus sleeve gastrectomy with transit bipartition—to see which leads to fewer digestive problems and better quality of life. About 200 adults with obesity will be followed for 6 months after surgery. T…

This study aimed to measure lung pressure in people with severe obesity to better understand breathing problems. Researchers planned to use a small balloon in the esophagus and chest CT scans in 12 adults. The study was withdrawn before enrolling anyone, so no results are availab…

This study follows 75 people who had either sleeve gastrectomy or gastric bypass surgery for severe obesity. Researchers want to see how many develop or continue to have acid reflux (GERD) over 8 years. No new treatments are given—this is just observation using questionnaires, en…