MORBID OBESITY
Clinical trials for MORBID OBESITY explained in plain language.
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New weight loss surgery shows promise in study
Disease control CompletedThis study looked at a newer type of weight loss surgery called SADI-S and compared it to a standard surgery for people with severe obesity. The goal was to see if SADI-S is safer and works as well or better for weight loss and related health problems. 62 adults took part, and re…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Sleeve surgery may help you walk better
Disease control CompletedThis study tested whether sleeve gastrectomy (a type of weight-loss surgery) improves walking ability in people with severe obesity. Researchers measured how far 99 participants could walk in 6 minutes before surgery and again 6 months after. They also checked quality of life usi…
Matched conditions: MORBID OBESITY
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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Smartphone app boosts pre-surgery weight loss in obesity trial
Symptom relief CompletedThis study tested whether a mobile app (Care4Today®) helps people with severe obesity lose weight before gastric bypass surgery. 142 adults used either the app or standard care. The goal was to see if the app leads to more weight loss and better patient knowledge and satisfaction…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospital Universitari de Bellvitge • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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Lidocaine infusion may cut opioid use after bariatric surgery
Symptom relief CompletedThis study tested whether giving the numbing drug lidocaine through a vein during weight-loss surgery could reduce pain and the need for strong painkillers afterward. 180 adults scheduled for bariatric surgery took part. Half received lidocaine, half a placebo. Researchers measur…
Matched conditions: MORBID OBESITY
Phase: PHASE3 • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated Jun 15, 2026 18:55 UTC
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Nerve block eases pain after sleeve gastrectomy, study finds
Symptom relief CompletedThis study looked at whether a specific nerve block (external oblique intercostal block) can reduce pain after laparoscopic sleeve gastrectomy, a weight-loss surgery. Twenty patients aged 18-65 were included. Researchers measured how much numbness the block caused and how much pa…
Matched conditions: MORBID OBESITY
Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 10, 2026 13:29 UTC
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Opioid-Free anesthesia shows promise for bariatric surgery patients
Symptom relief CompletedThis study tested whether avoiding opioids during weight-loss surgery can still control pain effectively. Sixty adults with severe obesity were randomly assigned to receive either opioid-free or standard opioid anesthesia. Researchers measured pain levels, need for extra pain med…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospital dos Lusíadas • Aim: Symptom relief
Last updated Jun 10, 2026 13:29 UTC
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Mist before surgery steadies heart in obese patients
Symptom relief CompletedThis study tested whether giving a medicated mist (dexmedetomidine) before surgery could prevent dangerous spikes in heart rate and blood pressure when placing a breathing tube in 90 obese patients undergoing laparoscopic bariatric surgery. The approach aims to make the procedure…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 03, 2026 12:06 UTC
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When you eat may reshape your gut bugs, study suggests
Knowledge-focused CompletedThis study looked at how the number of meals per day and the timing of calories affect the gut microbiome in 34 adults—11 non-obese and 23 with morbid obesity. Researchers analyzed diet records and gut bacteria samples to find links between eating patterns and microbial profiles.…
Matched conditions: MORBID OBESITY
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 16, 2026 23:20 UTC
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Stomach scans after bariatric surgery may predict weight regain
Knowledge-focused CompletedThis study looked at 46 people with severe obesity who had either gastric bypass or sleeve gastrectomy. Researchers used a special CT scan with gas to measure stomach volume 3 and 12 months after surgery. The goal was to see if an enlarged stomach pouch is linked to weight regain…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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Blood thinner behavior in obesity and after Weight-Loss surgery under the microscope
Knowledge-focused CompletedThis study looked at how the blood thinner rivaroxaban acts in people with severe obesity and in those who had weight-loss surgery (gastric bypass or sleeve gastrectomy) at least a year earlier. Sixty-seven participants took rivaroxaban for eight days, and researchers measured dr…
Matched conditions: MORBID OBESITY
Phase: PHASE1 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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Study seeks safer intubation for obese patients
Knowledge-focused CompletedThis study looked at 725 severely obese patients (BMI 35 or higher) to find the safest way to place a breathing tube during surgery. Researchers compared two methods: one with face mask ventilation during the procedure and one without. The goal was to see which approach caused fe…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:29 UTC
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Wearable tech reveals links between sitting and quality of life
Knowledge-focused CompletedThis study looked at how physical activity relates to quality of life and mental health in 38 adults with severe obesity (BMI over 40). Participants wore activity monitors for 6 weeks to track sitting, standing, and movement. The goal was to see if simply monitoring activity coul…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:05 UTC