MOBILITY DISABILITY

This Phase 2b trial tests whether adding enobosarm (a muscle-preserving drug) to semaglutide (a weight-loss drug) helps older adults lose more fat and keep muscle. About 200 people aged 65 and older who are overweight or obese will take both drugs or semaglutide alone. The goal i…

This study looks at whether adding a cocoa supplement to a regular exercise program helps older adults (55+) with slow walking speed improve their physical performance and muscle strength more than exercise alone. Participants will be randomly assigned to receive either cocoa or …

This study tests whether 6 months of daily, home-based transcranial direct current stimulation (tDCS) can improve cognitive and motor function in 128 older adults (ages 65-90) with motoric cognitive risk syndrome, a condition that raises dementia risk. Participants use a headset …

This study looks at why older adults respond differently to strength training. Researchers will enroll 300 people aged 65 and older who are at risk for mobility problems. Participants will either do progressive resistance training three times a week or attend weekly health educat…