MIGRAINE DISORDERS

This study aims to find the most effective way to prevent migraines in children and teens using telehealth. Researchers will compare cognitive behavioral therapy (CBT) delivered via video calls alone versus CBT combined with the medication amitriptyline. The trial involves 400 yo…

This study is testing if closing a common, small hole in the heart (called a PFO) can reduce migraine headaches. Researchers will compare migraine symptoms and brain scans in adults with migraines before and after the closure procedure. The goal is to see if this treatment helps …

This study is testing a new lifestyle and behavior program to help manage chronic migraine. Researchers will enroll 60 adults who have had chronic migraine for at least a year to see if the program is practical and acceptable. The main goals are to check if people can stick with …

This study is testing a mind-body skills program delivered by nurses to help children and teens (ages 10-17) with migraines reduce their headache days. Researchers are comparing different versions of the program to find the most effective combination of coaching sessions, home pr…

This study aims to better understand what causes migraine by investigating the immune system. Researchers will compare levels of specific immune cells and inflammatory signals in women with and without migraine, some of whom also have other autoimmune conditions. The goal is to g…

This study is creating a detailed registry of migraine patients in Italy to better understand how the disease affects people and how they navigate the healthcare system. Researchers will follow 2,030 adults with migraines for two years, collecting information about their symptoms…