METASTATIC SOFT TISSUE SARCOMA
Clinical trials for METASTATIC SOFT TISSUE SARCOMA explained in plain language.
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Three-Pronged attack on Tough-to-Treat sarcoma
Disease control OngoingThis study is testing if combining three different cancer drugs works better than standard care for advanced soft tissue sarcoma that has spread. It will involve about 105 adults whose cancer has worsened after one or two prior treatments. The goal is to see if this combination c…
Matched conditions: METASTATIC SOFT TISSUE SARCOMA
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Experimental cancer cocktails tested on tough tumors
Disease control OngoingThis early-stage trial is testing four different combinations of experimental drugs with existing cancer medications for people with metastatic solid tumors. The study aims to find safe doses and see if these combinations can shrink tumors in seven specific cancer types. It's des…
Matched conditions: METASTATIC SOFT TISSUE SARCOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New drug duo tested to halt aggressive sarcoma
Disease control OngoingThis study is testing whether combining two drugs, cabozantinib and temozolomide, can better control advanced soft tissue sarcomas that cannot be removed by surgery or have spread. The trial aims to see if this combination can stop the cancer from growing for longer and improve s…
Matched conditions: METASTATIC SOFT TISSUE SARCOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Scientists test Two-Drug attack on Tough-to-Treat sarcomas
Disease control OngoingThis study is testing the safety and early effectiveness of a new two-drug combination (HDM201 and pazopanib) for adults with advanced soft tissue sarcoma that has a specific genetic profile (p53 wild-type). The first part finds the safest dose, and the second part looks for earl…
Matched conditions: METASTATIC SOFT TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New Two-Drug attack on Tough-to-Treat sarcoma
Disease control OngoingThis study is testing whether adding a newer drug, lurbinectedin, to a standard chemotherapy (doxorubicin) works better for treating advanced soft-tissue sarcoma. The first part checks the safety and best dose of the combination. The second part directly compares the new combinat…
Matched conditions: METASTATIC SOFT TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New Three-Drug attack on tough sarcomas enters key test
Disease control OngoingThis study is testing if a three-drug combination works better than a two-drug immunotherapy approach to control advanced soft tissue sarcoma. It will involve about 66 adults with specific types of sarcoma that have spread or cannot be surgically removed. The goal is to see if ad…
Matched conditions: METASTATIC SOFT TISSUE SARCOMA
Phase: PHASE2 • Sponsor: National Cancer Institute LAO • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC