New drug combo shows promise for Hard-to-Treat sarcomas
NCT ID NCT04200443
First seen Jan 05, 2026 · Last updated Jun 08, 2026 · Updated 24 times
Summary
This study tests whether combining two drugs—cabozantinib and temozolomide—can help people with advanced soft tissue sarcomas (like leiomyosarcoma) that have spread or can't be removed by surgery. About 96 participants will receive the combination to see if it slows tumor growth. The goal is to improve disease control, not to cure the cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, 52242, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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