Promising drug combo targets rare sarcoma in early trial
NCT ID NCT05099666
First seen Jan 06, 2026 · Last updated May 13, 2026 · Updated 18 times
Summary
This study tests a new combination of two drugs, lurbinectedin and doxorubicin, for people with advanced leiomyosarcoma, a rare soft tissue cancer. The first part finds a safe dose, and the second part compares the combination to lurbinectedin alone to see which works better. About 62 adults with no other treatment options are taking part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02115, United States
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Mayo Arizona
Phoenix, Arizona, 85054, United States
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Mayo Jacksonville
Jacksonville, Florida, 32224, United States
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Mayo Rochester
Rochester, Minnesota, 55905, United States
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Memorial Sloan Kettering
New York, New York, 10065, United States
Conditions
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