MELANOMA (SKIN)

This study tested the drug nivolumab in 26 people with stage IIB or IIC melanoma that had been completely removed by surgery. The goal was to see if nivolumab, an immunotherapy that helps the immune system attack cancer cells, could prevent the melanoma from coming back. Particip…

This study tested a new approach for stage IIIB/C melanoma, the deadliest form of skin cancer. Nineteen participants received a single infusion of the immunotherapy drug nivolumab, followed by cryotherapy (freezing) of a cancerous lymph node, and then an injection of another immu…

This study tested whether adding denosumab (a bone-strengthening drug) to standard immunotherapy (pembrolizumab or nivolumab) could help control advanced melanoma that has spread. Researchers enrolled 25 adults with stage III or IV melanoma who had not received prior immunotherap…

This study tested whether an artificial intelligence (AI) system can help detect melanoma, a dangerous form of skin cancer. Researchers took photos of suspicious skin spots from 105 adults using a smartphone camera and let the AI analyze them. They compared the AI's results to di…

This study looked at whether giving people personalized information about their genetic risk for melanoma could encourage them to protect themselves from the sun. Over 2,000 adults received either standard sun safety tips or tailored advice based on their DNA. Researchers then tr…

This study tested Emotional Freedom Techniques (EFT), a therapy that combines talking with gentle tapping on acupressure points, in 56 people who had been treated for melanoma and were in remission. The goal was to see if EFT could reduce fear of the cancer coming back and improv…

This study brought together four expert skin pathologists to see how well they agree when diagnosing moles that might be melanoma. The goal was to create a reliable standard for future research. The experts reviewed images and discussed tricky cases to reach a consensus.

This study explored whether lab-grown skin models containing a patient's own melanoma cells could predict which drug combinations would work best. Researchers took a small sample of a skin metastasis and used it to create 3D cultures and artificial skin. The goal was to test diff…

This study followed about 400 adults with advanced BRAF-mutant melanoma who were taking targeted therapy (BRAF/MEK inhibitors) and using a smartphone app called TavieSkin. The goal was to describe patient characteristics, how they used the app, their quality of life, and treatmen…

This early-phase trial tested a special PET/CT imaging agent, Zirconium Zr 89 Crefmirlimab Berdoxam, to see if it can measure immune activity in tumors of patients with advanced melanoma. Six adults on immunotherapy plus hydroxychloroquine received scans before and after starting…