Skin in a dish could predict best melanoma drugs

NCT ID NCT03136783

Completed Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explored whether lab-grown skin models containing a patient's own melanoma cells could predict which drug combinations would work best. Researchers took a small sample of a skin metastasis and used it to create 3D cultures and artificial skin. The goal was to test different targeted therapy drugs on these models to see which ones killed the cancer cells most effectively, potentially allowing doctors to personalize treatment and avoid unnecessary side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this approach could help doctors choose the most effective targeted therapy for each melanoma patient, reducing trial-and-error and side effects.
What could go wrong: This was a very small, early study with only one participant. The lab models may not accurately predict real patient responses, and more research is needed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELANOMA (SKIN)

Contacts and locations

Locations

CHU Amiens Picardie

Amiens, Picardie, 80054, France

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