MEDULLOBLASTOMA, CHILDHOOD
Clinical trials for MEDULLOBLASTOMA, CHILDHOOD explained in plain language.
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Custom immune cells take aim at childhood brain cancers
Disease control Recruiting nowThis early-phase study tests a personalized treatment for children under 5 with certain brain tumors. Doctors take a patient's own immune cells, train them to recognize unique markers from their tumor, and give them back to fight the cancer. The goal is to see if this approach is…
Matched conditions: MEDULLOBLASTOMA, CHILDHOOD
Phase: PHASE1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated May 17, 2026 02:07 UTC
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Engineered immune cells injected directly into the brain show promise for childhood cancers
Disease control Recruiting nowThis early-stage study is testing whether specially engineered immune cells (CAR T cells) can be safely given directly into the brain or spinal fluid of children and young adults with aggressive brain tumors like DIPG or recurrent medulloblastoma. The cells are designed to recogn…
Matched conditions: MEDULLOBLASTOMA, CHILDHOOD
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New hope for toddlers with rare brain cancers: targeted chemo trial launches
Disease control Recruiting nowThis early-phase study tests whether adding a chemotherapy drug (topotecan) given directly into the spinal fluid, followed by maintenance chemo, is safe and feasible for children under 6 with high-risk embryonal brain tumors. About 15 children will participate. The goal is to see…
Matched conditions: MEDULLOBLASTOMA, CHILDHOOD
Phase: EARLY_PHASE1 • Sponsor: C17 Council • Aim: Disease control
Last updated May 12, 2026 13:48 UTC
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Video workouts tested for young brain tumor survivors
Symptom relief Recruiting nowThis study tests whether children and teens who have finished treatment for medulloblastoma can do exercise sessions through video calls. The program lasts 12 weeks with three personalized sessions per week. Researchers want to see if this approach is practical, safe, and helpful…
Matched conditions: MEDULLOBLASTOMA, CHILDHOOD
Phase: NA • Sponsor: Aron Onerup • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Diabetes drug shows promise for Kids' brain recovery after tumor treatment
Symptom relief Recruiting nowThis study tests whether metformin, a drug used for diabetes, can help children and teens recover memory and thinking skills after brain tumor treatment. About 140 participants aged 7 to 21 will take metformin or a placebo for 16 weeks. The goal is to see if the drug improves mem…
Matched conditions: MEDULLOBLASTOMA, CHILDHOOD
Phase: PHASE3 • Sponsor: Donald Mabbott • Aim: Symptom relief
Last updated May 12, 2026 13:41 UTC
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Tailored tumor testing aims to match kids with best drugs
Knowledge-focused Recruiting nowThis study is testing a new approach for children and young adults whose medulloblastoma or ependymoma has come back. After surgery, the tumor is quickly tested in the lab and its genes are analyzed to find the most effective and least toxic drugs for that specific patient. A spe…
Matched conditions: MEDULLOBLASTOMA, CHILDHOOD
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC