MALIGNANT SOLID TUMORS

This study tests a new drug called SHR-7787 combined with other cancer treatments in people with advanced solid tumors that cannot be removed by surgery. The goal is to find safe doses and see if the combination shrinks tumors or slows cancer growth. About 400 adults with various…

This study tests a drug called asciminib in people with chronic myeloid leukemia (CML) whose first treatment did not work well or caused side effects. The goal is to see if asciminib can lower cancer signals in the blood to very low levels within 12 months. About 40 adults will t…

This study tests a new drug called SHR-4849 combined with other cancer medicines in people with advanced solid tumors. The goal is to see if the combination is safe and can shrink tumors. About 120 adults aged 18 to 75 with measurable tumors and adequate organ function will parti…

This study tests a new drug called TAK-505 for the first time in people with advanced solid tumors that cannot be removed by surgery. The main goals are to check the drug's safety, find the best dose, and see if it can shrink or slow tumor growth. About 151 adults with certain ca…

This study tests an experimental drug called SHR-1681 in about 300 adults whose advanced solid tumors have not responded to standard treatments. The main goals are to find the safest dose and to check for side effects. Researchers will also measure how the drug moves through the …

This study is testing a new type of MRI scan that uses a special imaging agent called hyperpolarized pyruvate. The goal is to see if the scan results are the same each time it is done for the same person. About 109 people with solid tumors will have two of these scans, and the re…

This study aims to better understand rare solid tumors by collecting biological samples (like blood, saliva, and tumor tissue) and health information from up to 10,000 people over many years. Participants include people with a rare tumor, those with a genetic risk for one, and th…