New cancer drug TAK-505 enters first human trials
NCT ID NCT07436728
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new drug called TAK-505 in adults with advanced solid tumors that cannot be removed by surgery. The main goals are to check safety, find the best dose, and see if the drug can shrink or slow cancer growth. About 151 people with certain cancers, such as stomach, colorectal, lung, or head and neck cancers, will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
TAK-505
What this could lead to
If successful, this could point toward a new treatment option for certain advanced solid tumors like stomach, colorectal, lung, or head and neck cancers.
What could go wrong
This is an early first-in-human trial, so the drug may not work or could have unexpected side effects. The results are preliminary and may not lead to a widely available treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baylor College of Medicine
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic Foundation
NOT_YET_RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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H Lee Moffitt Cancer Center
NOT_YET_RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Icahn School of Medicine at Mount Sinai
NOT_YET_RECRUITINGNew York, New York, 10029, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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MD Anderson
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mary Crowley Cancer Center
NOT_YET_RECRUITINGDallas, Texas, 75230, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NEXT Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NEXT Oncology
RECRUITINGFairfax, Virginia, 22031, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sarah Cannon Research Institute SCRI
NOT_YET_RECRUITINGNashville, Tennessee, 37203, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Seattle Cancer Care Alliance
NOT_YET_RECRUITINGSeattle, Washington, 98109, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tennessee Oncology
NOT_YET_RECRUITINGNashville, Tennessee, 37203, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCI Health
NOT_YET_RECRUITINGOrange, California, 92868, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Univeristy of Minnesota
NOT_YET_RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Diego Medical Center, La Jolla
NOT_YET_RECRUITINGSan Diego, California, 92093, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco
NOT_YET_RECRUITINGSan Francisco, California, 94143, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••