MAJOR DEPRESSIVE EPISODE
Clinical trials for MAJOR DEPRESSIVE EPISODE explained in plain language.
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New ECT method may reduce memory loss in depression treatment
Symptom relief CompletedThis study tested two ways of giving electroconvulsive therapy (ECT) to 156 people with severe depression. One method uses a frontoparietal placement and the other uses a temporoparietal placement. The goal was to see if the frontoparietal method works as well but causes fewer me…
Matched conditions: MAJOR DEPRESSIVE EPISODE
Phase: NA • Sponsor: The George Institute • Aim: Symptom relief
Last updated May 17, 2026 06:23 UTC
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Texting away the baby blues: new study tests simple phone messages to protect new moms
Symptom relief CompletedThis study tested a text messaging program designed to lower the risk of major depression in pregnant and new mothers. 40 women who were at risk but not currently depressed received tailored texts with links to helpful content and a chat feature to talk with other participants. T…
Matched conditions: MAJOR DEPRESSIVE EPISODE
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 11, 2026 20:39 UTC
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Blood protein may reveal who benefits from depression drug
Knowledge-focused CompletedThis study looked at whether certain proteins called beta-arrestins can help predict how well people with major depression will respond to the antidepressant venlafaxine. Researchers measured these proteins in blood samples and tracked depression symptoms over three months in 67 …
Matched conditions: MAJOR DEPRESSIVE EPISODE
Phase: PHASE4 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 17, 2026 06:20 UTC
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Study tracks PTSD in survivors of major terror attacks
Knowledge-focused CompletedThis study followed 14 people who called a crisis hotline after terrorist attacks in Paris, London, Barcelona, and Strasbourg. Researchers wanted to see how their mental health symptoms, like post-traumatic stress disorder and depression, changed over time. The goal was to learn …
Matched conditions: MAJOR DEPRESSIVE EPISODE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Scientists hunt for genetic clues in depression
Knowledge-focused CompletedThis study looked at 30 people—some with major depression and some without—to see if certain genes are turned on or off differently. Researchers checked blood samples over time to track how these gene changes might relate to the course of depression. The goal was to better unders…
Matched conditions: MAJOR DEPRESSIVE EPISODE
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated May 13, 2026 16:04 UTC