MAJOR DEPRESSIVE EPISODE
Clinical trials for MAJOR DEPRESSIVE EPISODE explained in plain language.
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Brain shock therapy tested: new method aims to preserve memories while fighting depression
Disease control CompletedThis study tested two different ways of giving electroconvulsive therapy (ECT) to people with severe depression. Researchers wanted to see if placing the electrodes in a different spot on the head (frontoparietal) works as well as the standard spot (temporoparietal) but causes fe…
Matched conditions: MAJOR DEPRESSIVE EPISODE
Phase: NA • Sponsor: The George Institute • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Texting away the baby blues: simple messages aim to stop depression before it starts
Prevention CompletedThis study tested whether a simple text messaging program could help prevent depression in pregnant women and new mothers. Researchers sent daily supportive texts, links to helpful videos, and offered a chat with a trained peer to 40 participants who were at risk for depression. …
Matched conditions: MAJOR DEPRESSIVE EPISODE
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Prevention
Last updated Mar 31, 2026 12:12 UTC
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Tracking trauma: how attack survivors fared after calling crisis lines
Knowledge-focused CompletedThis study followed people who called emergency psychological hotlines after major terrorist attacks in Paris, London, Barcelona, and Strasbourg. Researchers wanted to understand how their mental health symptoms changed over time and what kind of help they were looking for. The s…
Matched conditions: MAJOR DEPRESSIVE EPISODE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists hunt for blood test to predict antidepressant success
Knowledge-focused CompletedThis study aimed to find biological markers that could predict who will respond well to the antidepressant venlafaxine. Researchers followed 60 people with major depression and 20 healthy volunteers for three months. They measured specific proteins in the blood and linked them to…
Matched conditions: MAJOR DEPRESSIVE EPISODE
Phase: PHASE4 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC