LYMPHEDEMA

This study tests whether a ketogenic diet (low-carb, high-fat) or ketone supplements can improve lymph vessel function and reduce swelling in people with lymphedema after arm lymph node surgery. About 81 adults with early-stage lymphedema will be randomly assigned to a ketogenic …

This study is testing a robotic system called Symani to help surgeons perform delicate microsurgery for two types of procedures: free tissue transfer (moving tissue from one part of the body to another) and lymphatic surgery (to treat lymphedema, a condition causing swelling). Ab…

This study uses special ultrasound techniques to find clear differences between lymphedema and lipedema, two chronic conditions that cause leg swelling and are often hard to tell apart. Researchers will compare 75 adults—those with lymphedema, those with lipedema, and healthy vol…

This study tests if repairing the lymphatic system during breast cancer surgery can prevent lymphedema, a painful arm swelling. 50 women with breast cancer will receive this reconstruction. The goal is to see if this approach reduces the risk of developing lymphedema.

This study tests a procedure called LYMPHA, done at the same time as breast cancer lymph node removal, to see if it can prevent lymphedema—a chronic, painful arm swelling. About 80 women having breast cancer surgery will be randomly assigned to receive LYMPHA or standard care. Re…

This study tests whether adding virtual reality (VR) exercises to standard therapy can improve walking, daily function, and quality of life in people with chronic leg swelling (lymphedema) after cancer surgery. About 40 adults aged 18-65 with stage 2 or 3 lymphedema will use a VR…

This study is testing a new portable, non-pneumatic compression device for people with lymphedema or phlebolymphedema (leg swelling due to vein problems). About 100 VA patients will use the device to see if it improves mobility, reduces swelling, and lowers healthcare costs compa…

This study tests if progressive resistance exercise can improve arm swelling and function in people who developed lymphedema after breast cancer treatment. Fifty adults aged 18-60 who are at least 3 months past surgery will be enrolled. Participants will do supervised exercises a…

This study looks at whether resistance exercise (like leg presses) can reduce swelling in people with lower limb lymphedema, and whether wearing compression garments during exercise makes a difference. About 36 adults with confirmed lymphedema will do supervised resistance traini…

This study is creating a collection of blood, urine, and stool samples from 500 adults with or at risk for heart and blood vessel diseases. Researchers will use these samples to study inflammation, blood clotting, and other biological pathways. The goal is to build a resource tha…

This study follows 100 women with early-stage breast cancer for two years after surgery and other treatments. Researchers will measure changes in muscle mass and body fat using a special scale. The goal is to understand how the body changes during recovery, which may help improve…