LIPOSARCOMA

This early-stage study tests a new drug called BTX-A51 in 24 people with advanced liposarcoma that has spread or come back. The main goal is to check if the drug is safe and tolerable at two different doses. Researchers will also watch for any tumor shrinkage or slowing of the di…

This study tests a new treatment called AGAR T cells for children whose solid tumors (like liver cancer or Wilms tumor) have returned or not responded to standard care. The treatment involves taking a patient's own immune cells, adding genes to help them recognize and attack tumo…

This study tests a combination of a cancer-killing virus (T-VEC) and radiation therapy in 40 adults with newly diagnosed soft tissue sarcoma that can be surgically removed. The goal is to see if this approach destroys more tumor cells before surgery and to check for side effects.…

This study looks at whether adding the drug pazopanib to standard radiation or chemoradiation helps shrink soft tissue sarcomas before they are removed surgically. About 140 adults and children with newly diagnosed, high-risk sarcomas that can be operated on are participating. Th…

This study tests a new drug called PF-07220060 in people with advanced solid tumors, including breast, prostate, lung, and liposarcoma cancers. The drug is given alone or with hormone therapies to see if it is safe and works well. About 362 participants will take part to find the…

This early-stage trial tests a new treatment called CATCH T cells for people with certain solid tumors that have come back or not responded to standard care. The treatment involves taking a patient's own immune cells, adding new genes to help them recognize and attack cancer cell…

This early-stage trial tests the safety and best dose of the chemotherapy drug eribulin given together with radiation before surgery for a rare cancer called retroperitoneal liposarcoma. About 15 adults with this tumor will receive the combination to see how well they tolerate it…