New drug combo shows promise for Hard-to-Treat cancers
NCT ID NCT04557449
First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 28 times
Summary
This study tests a new drug called PF-07220060 in people with advanced solid tumors, including breast, prostate, lung, and liposarcoma cancers. The drug is given alone or with hormone therapies to see if it is safe and works well. About 362 participants will take part to find the best dose and measure how the drug affects their cancer.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham & Women's Hospital
Boston, Massachusetts, 02115, United States
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COI Centro Oncologico Internacional S.A.P.I. de C.V.
Mexico City, Mexico City, Mexico
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Cancer Hospital Chinese Academy of Medical Science
Beijing, Beijing Municipality, 100021, China
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Cancer Research UK Edinburgh Centre
Edinburgh, Edinburgh, CITY of, EH4 2XR, United Kingdom
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Clínica Universitaria Reina Fabiola
Córdoba, X50004FHP, Argentina
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Dana Farber Cancer Institute- Chestnut Hill
Newton, Massachusetts, 02459, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Ellison Institute
Los Angeles, California, 90064, United States
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Fakultna nemocnica s poliklinikou Nove Zamky
Nové Zámky, 940 34, Slovakia
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Fakultni nemocnice Olomouc
Olomouc, 779 00, Czechia
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Fundación CORI para la Investigación y Prevención del Cáncer
La Rioja, F5300COE, Argentina
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Fundación Cenit Para La Investigación En Neurociencias
CABA, Ciudad Autã³noma de Buenos Aires, 1125, Argentina
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Fundación Respirar
Buenos Aires, C1426ABP, Argentina
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Henan Cancer Hospital
Zhengzhou, Henan, 450008, China
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Hospital Británico de Buenos Aires
Ciudad Autónoma de Buenos Aires, Buenos Aires, 1280, Argentina
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Hospital MAC Periferico Sur
Mexico City, Mexico City, 04700, Mexico
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Hospital Reforma
Oaxaca City, Oaxaca, 68000, Mexico
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Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
Monterrey, Nuevo León, 64460, Mexico
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Hubei Cancer Hospital
Wuhan, Hubei, 430079, China
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INCAN
Mexico City, Mexico City, 14080, Mexico
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Narodny onkologicky ustav
Bratislava, 833 10, Slovakia
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National Cancer Center Hospital East
Kashiwa, Chiba, 277-8577, Japan
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Oaxaca Site Management Organization
Oaxaca City, 68000, Mexico
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Onkologicky ustav sv. Alzbety, s.r.o., Interna klinika VSZaSP a OUSA
Bratislava, 812 50, Slovakia
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POKO Poprad, s.r.o.
Poprad, 058 01, Slovakia
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SCRI Oncology Partners
Nashville, Tennessee, 37203, United States
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START Midwest
Grand Rapids, Michigan, 49546, United States
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Sarah Cannon Research Institute - Pharmacy
Nashville, Tennessee, 37203, United States
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Sarah Cannon Research Institute UK
London, W1G 6AD, United Kingdom
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310016, China
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Smilow Cancer Hospital Phase 1 Unit
New Haven, Connecticut, 06511, United States
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Smilow Cancer Hospital at Yale - New Haven
New Haven, Connecticut, 06510, United States
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St Bartholomew's Hospital
London, London, CITY of, EC1A 7BE, United Kingdom
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The Christie Hospital NHS Foundation Trust
Manchester, M20 4BX, United Kingdom
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The First Affiliated Hospital of Xi'an Jiaotong University
Xi’an, Shanxi, 710061, China
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Vseobecna fakultni nemocnice v Praze
Prague, 12808, Czechia
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Yale-New Haven Hospital-Yale Cancer Center
New Haven, Connecticut, 06510, United States
Conditions
Explore the condition pages connected to this study.