INTERSTITIAL LUNG DISEASE (ILD)

This study tests whether adding a new inhaled drug, mosliciguat, to an existing treatment (treprostinil) is safe for people with high blood pressure in the lungs caused by lung scarring. About 20 adults with this condition will receive the combination and be monitored for side ef…

This study tests whether tetrandrine tablets can improve lung function in adults with connective tissue disease-related interstitial lung disease (a type of lung scarring). About 100 participants will receive either tetrandrine or a placebo, on top of their usual medications, for…

This study looks at two ways of using a heart-lung machine (ECMO) during lung transplants: using it for every patient or only when needed. The goal is to find out which method leads to fewer complications and better recovery. About 218 adults getting a lung transplant will take p…

This study tests whether using a robot to guide a lung biopsy helps doctors get a clearer diagnosis for interstitial lung disease (ILD) compared to the standard method. About 30 adults with suspected ILD will be randomly assigned to one of two biopsy techniques. The goal is to se…

This study tests whether an artificial intelligence (AI) tool can analyze a simple ECG to detect undiagnosed pulmonary hypertension (high blood pressure in the lungs) in people with interstitial lung disease. About 900 adults with severe lung scarring will be randomly assigned to…

This study tests a new way to organize follow-up care for people with interstitial lung disease (ILD). Instead of making several separate trips for tests, lab work, and doctor visits, the new approach bundles everything into one coordinated hospital visit. The goal is to reduce t…

This study tests whether L-menthol, a minty compound, can reduce breathlessness and help people with interstitial lung disease (ILD) exercise longer. Twenty adults with ILD will try L-menthol and a placebo in random order to compare effects. The goal is to find a simple, safe way…

This study looks at whether people with pulmonary fibrosis can use home monitoring and video calls instead of half their regular clinic visits. The goal is to see if this helps patients manage their own health better. About 220 adults with pulmonary fibrosis will take part, and r…

This study tests whether bundling key tests (like CT scans and lung function tests) into a single, fast-tracked appointment can help people with suspected interstitial lung disease get a diagnosis sooner. About 92 adults will be randomly assigned to either the usual step-by-step …

This early-stage study tests a single inhaled dose of RJ026 in 42 healthy volunteers and 42 people with interstitial lung disease (ILD), a type of lung scarring. The goal is to measure how much drug gets into the blood and lungs, and to check for side effects over 7 days. No trea…