Lung transplant study tests whether ECMO should be used routinely or only when needed

NCT ID NCT06615492

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways of using a heart-lung support machine (ECMO) during lung transplants: using it routinely for all patients versus using it only when problems arise. About 218 adults with end-stage lung disease will take part. The goal is to see which approach leads to more days free from intensive care and fewer complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Extracorporeal membrane oxygenation (ECMO) device

What this could lead to

If it works, this could show that using ECMO only when needed is safer and just as effective as using it routinely, potentially reducing complications like bleeding and infection.

What could go wrong

This is a single-center trial with 218 participants, so results may not apply to all hospitals. ECMO itself carries risks like bleeding and clotting, and the selective approach might not prevent severe complications in some patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset interstitial lung disease pulmonary fibrosis respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier de l'Universite de Montreal

    RECRUITING

    Montreal, Quebec, H2X3E4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Univeristy of Alberta & Alberta Health Services

    NOT_YET_RECRUITING

    Edmonton, Alberta, T6G2G3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Health Network / Toronto General Hospiatl

    NOT_YET_RECRUITING

    Toronto, Ontario, M5G 1M1, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vancouver General Hospital

    NOT_YET_RECRUITING

    Vancouver, British Columbia, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••