INFECTIOUS DISEASE

This study is testing if a nutritional supplement called L-Citrulline can help young children hospitalized with serious infections. About 888 children in Mozambique and Ethiopia who are at high risk for severe complications will receive either the L-Citrulline syrup or a placebo …

This study is testing a personalized approach to dosing an antifungal drug called voriconazole for patients with blood cancer. It compares using a patient's genetic test results to guide dosing against the current standard method. The goal is to see if the personalized method hel…

This study is testing if a new, rapid finger-prick blood test can help doctors make better decisions when a young child arrives with a fever. It will compare the new test, used alongside current guidelines, against the guidelines alone to see which method more accurately identifi…

This international study aims to better understand how acute infections affect hospitalized adults by observing 1,500 patients across multiple countries. Researchers will collect health data and biological samples to learn about risk factors, disease patterns, and recovery timeli…

This early-stage study aims to test the safety of giving high doses of the antiviral drug favipiravir to healthy volunteers for 14 days. Researchers will closely monitor participants for side effects and measure how the drug moves through and is processed by the body, including i…

This study is creating a large international registry to collect real-world data on how a medical device called CytoSorb is used in critical care. The device filters harmful substances from a patient's blood and is used for various severe conditions like septic shock, severe trau…