INFECTIOUS DISEASE

This study tests whether giving L-Citrulline syrup for 28 days can reduce serious complications (like death, organ failure, or readmission) in children aged 1 month to 5 years who are hospitalized with fever and identified as high-risk by a rapid blood test. About 888 children in…

This study tests whether using a patient's genetic information to dose the antifungal drug voriconazole can help more patients reach the right drug level in their blood compared to standard dosing. The trial will enroll about 104 children and adults with blood cancer or fungal in…

This study tests a new rapid triage test for children with fever in sub-Saharan Africa. The goal is to see if adding this test to standard care helps doctors better decide which children need hospital admission and which can go home safely. About 5,200 children aged 2 months to 5…

This study will follow 1,500 adults admitted to the hospital with a suspected or confirmed acute infection. Researchers will collect data and samples to understand risk factors, symptoms, and how the disease progresses. The goal is to use this information to design better treatme…

This study tests the safety of high doses of favipiravir, an antiviral drug, in 39 healthy volunteers. Participants receive different dose levels for 14 days to see how well the body handles the drug and how it is processed. The goal is to gather safety and drug-level information…

This study is a large registry that collects data on how a blood-filtering device called CytoSorb is used in real-world intensive care settings. It will include up to 3,000 critically ill patients with conditions like septic shock, severe lung injury, or liver failure. The goal i…