Hunting the genes that make severe infections worse

NCT ID NCT06102070

Recruiting now Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study investigates why only some people develop severe infections from common germs. Researchers will analyze blood and skin samples from 2,000 participants with rare, serious infections to find genetic differences that may weaken immune defenses. The goal is to identify specific genes responsible for susceptibility, which could lead to better diagnosis and future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could identify new genes linked to severe infections, paving the way for better treatments and personalized care.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to new therapies, and findings may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFECTIOUS DISEASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Centre d'Etudes des Déficits Immunitaires (CEDI), Hôpital Necker-Enfants
RECRUITING

Paris, Île-de-France Region, 75015, France

Contact Phone: •••-•••-•••• Email: •••••@•••••

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