HYPERTROPHIC CARDIOMYOPATHY (HCM)

This study looks at whether people with a type of heart disease called obstructive hypertrophic cardiomyopathy can safely switch from one medication (mavacamten) to another (aficamten). The goal is to keep the heart working better and reduce symptoms. About 40 adults who are alre…

This study tests a new radioactive dye called 68Ga-NI-FAPI for PET/CT scans. It aims to better detect diseases like tumors, heart problems, and lung scarring by targeting a protein linked to tissue damage. About 30 people, including healthy volunteers and patients, will take part…

This study uses artificial intelligence to analyze standard electrocardiograms (ECGs) to accurately diagnose hypertrophic cardiomyopathy (HCM), a condition where the heart muscle thickens. The AI will also help tell HCM apart from other diseases that look similar, like high blood…

This study tests whether the blood thinner rivaroxaban can prevent strokes, heart attacks, and death in people with hypertrophic cardiomyopathy (HCM) who have early signs of atrial damage but normal heart rhythm. About 532 adults aged 40-80 with HCM and reduced left atrial strain…

This study is a national registry in the UK that collects health information from 2500 people with hypertrophic cardiomyopathy (HCM), a common inherited heart condition. Researchers will gather data from medical records, heart scans, blood tests, and genetics to better understand…

This study follows up on people with hypertrophic cardiomyopathy (HCM), a genetic condition that thickens the heart muscle. Researchers want to see how scarring in the heart (called late gadolinium enhancement, or LGE) changes over at least 7 years and whether it predicts serious…

This study looks back at medical records of 100 children with a genetic condition called RASopathy that causes severe heart thickening and heart failure. Researchers want to collect detailed information on how the disease progressed in the past. This will help design future studi…

This study looks at heart tissue samples from 216 adults who already need a biopsy as part of their care. Researchers want to find unique molecular patterns in different heart conditions, including after a heart transplant. The goal is to improve how these diseases are diagnosed …

This study will use cardiac MRI scans to measure heart tissue in 2000 people with various heart conditions, such as heart attacks, cardiomyopathies, and myocarditis. The goal is to create a reference map of normal and abnormal tissue values, which may help doctors diagnose diseas…