HYPERTROPHIC CARDIOMYOPATHY (HCM)
Clinical trials for HYPERTROPHIC CARDIOMYOPATHY (HCM) explained in plain language.
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Your genes may hold the key to your heart Drug's success
Disease control Not yet recruitingThis study aims to understand why a heart medication called mavacamten works better for some people with hypertrophic cardiomyopathy (HCM) than others. Researchers will follow 140 adults with HCM to see if the specific gene causing their condition or a gene that affects how the b…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY (HCM)
Sponsor: University of Manchester • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New heart drug tested in Real-World patients
Disease control Not yet recruitingThis study aims to see how well the drug mavacamten works for people with a specific form of hypertrophic cardiomyopathy (HCM), where the heart muscle is abnormally thick and causes a blockage in the middle or tip of the heart's main pumping chamber. It will involve 132 adult pat…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY (HCM)
Phase: PHASE4 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Major trial aims to stop silent strokes in heart patients before It's too late
Prevention Not yet recruitingThis large study is testing if a common blood thinner (rivaroxaban) can prevent strokes and other serious complications in people with hypertrophic cardiomyopathy (HCM), a genetic heart condition. It focuses on over 500 patients who are in normal heart rhythm but show early signs…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY (HCM)
Phase: PHASE3 • Sponsor: Rennes University Hospital • Aim: Prevention
Last updated Mar 31, 2026 12:11 UTC
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Scientists scan hearts to unlock secret of new Drug's power
Knowledge-focused Not yet recruitingThis study aims to understand how a newer heart medication (mavacamten) works in people with obstructive hypertrophic cardiomyopathy (HCM), a condition where the heart muscle thickens and obstructs blood flow. Researchers will use a specialized, non-invasive MRI scan to measure t…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY (HCM)
Sponsor: University of Manchester • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists probe why heart treatments fail in common genetic condition
Knowledge-focused Not yet recruitingThis study aims to understand why a type of irregular heartbeat (atrial fibrillation) is more common and harder to treat in people with a genetic condition that causes thickened heart muscle (hypertrophic cardiomyopathy). Researchers will study 40 adults with both conditions usin…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY (HCM)
Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Massive heart study aims to predict best treatments for thousands
Knowledge-focused Not yet recruitingThis study is creating a large UK database to collect health information from 2,500 people with hypertrophic cardiomyopathy (HCM), a common inherited heart condition. By tracking patients' health data over several years, researchers aim to better understand the disease and learn …
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY (HCM)
Sponsor: University of Manchester • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC