Gene secrets could explain why heart drug works for some, not others
NCT ID NCT07408427
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find out why the heart medication mavacamten works better for some people with hypertrophic cardiomyopathy (a condition where the heart muscle is too thick) than for others. Researchers will look at participants' genes, including the specific gene causing their condition and a gene called CYP2C19 that affects how the body processes drugs. The goal is to predict who will benefit most from the medication, leading to more personalized treatment. About 140 adults with this condition will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Manchester Centre for Genomic Medicine (MCGM)
Multiple Locations, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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