Gene secrets could explain why heart drug works for some, not others

This study aims to find out why the heart medication mavacamten works better for some people with hypertrophic cardiomyopathy (a condition where the heart muscle is too thick) than for others. Researchers will look at participants' genes, including the specific gene causing their condition and a gene called CYP2C19 that affects how the body processes drugs. The goal is to predict who will benefit most from the medication, leading to more personalized treatment. About 140 adults with this condition will take part.