Heart scarring over time: new study aims to predict sudden death risk in HCM patients

NCT ID NCT07054073

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows up on people with hypertrophic cardiomyopathy (HCM), a genetic condition that thickens the heart muscle. Researchers want to see how scarring in the heart (called late gadolinium enhancement, or LGE) changes over at least 7 years and whether it predicts serious problems like sudden cardiac arrest or heart failure. About 314 participants from an earlier study will get repeat MRI scans to track these changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Brigham & Women's Hospital

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • London Chest Hospital

    NOT_YET_RECRUITING

    London, E2 9JX, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern

    NOT_YET_RECRUITING

    Evanston, Illinois, 60208, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tufts Medical Center

    NOT_YET_RECRUITING

    Medford, Massachusetts, 02155, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospitals Birmingham NHS Foundation Trust

    NOT_YET_RECRUITING

    Birmingham, B15 2GW, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••