Heart scarring over time: new study aims to predict sudden death risk in HCM patients

NCT ID NCT07054073

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows up on people with hypertrophic cardiomyopathy (HCM), a genetic condition that thickens the heart muscle. Researchers want to see how scarring in the heart (called late gadolinium enhancement, or LGE) changes over at least 7 years and whether it predicts serious problems like sudden cardiac arrest or heart failure. About 314 participants from an earlier study will get repeat MRI scans to track these changes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham & Women's Hospital

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

  • London Chest Hospital

    NOT_YET_RECRUITING

    London, E2 9JX, United Kingdom

  • Northwestern

    NOT_YET_RECRUITING

    Evanston, Illinois, 60208, United States

  • Tufts Medical Center

    NOT_YET_RECRUITING

    Medford, Massachusetts, 02155, United States

  • University Hospitals Birmingham NHS Foundation Trust

    NOT_YET_RECRUITING

    Birmingham, B15 2GW, United Kingdom

  • University of Michigan

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

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