HYPERTROPHIC CARDIOMYOPATHY
Clinical trials for HYPERTROPHIC CARDIOMYOPATHY explained in plain language.
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Tiny heart device trial tests safer shock delivery
Disease control CompletedThis small pilot study aimed to see if a larger trial is possible to compare two types of life-saving heart defibrillators. It involved 5 patients with a thickened heart muscle condition (hypertrophic cardiomyopathy) who needed a defibrillator but not a pacemaker. The goal was to…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: NA • Sponsor: Barts & The London NHS Trust • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Heart drug's long-term safety tracked in follow-up study
Disease control CompletedThis study monitored the long-term safety of mavacamten, a medication for hypertrophic cardiomyopathy (a condition where the heart muscle thickens). It included 314 adults who had already completed earlier trials testing this drug. Researchers tracked side effects and safety over…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: PHASE2, PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Heart drug trial offers new hope for inherited heart condition
Disease control CompletedThis study tested whether a drug called trientine, already used for a different copper-related disease, could help people with hypertrophic cardiomyopathy (HCM), a condition where the heart muscle thickens. For 12 months, 154 adult patients with HCM received either trientine or a…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: PHASE2 • Sponsor: Manchester University NHS Foundation Trust • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Heart drug tested in people with kidney problems
Knowledge-focused CompletedThis study examined how HRS-1893, an experimental medication for hypertrophic cardiomyopathy, behaves in people with reduced kidney function compared to healthy people. Researchers measured drug levels in the blood of 24 participants to understand how kidney impairment affects th…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: PHASE1 • Sponsor: Shandong Suncadia Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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First human test for potential heart disease drug
Knowledge-focused CompletedThis was a very early study to see how a new oral drug called HRS-1893 behaves in the body and if it is safe. It involved 20 healthy volunteers who took a single dose. The main goal was to measure how the drug is absorbed, processed, and eliminated, and to check for any side effe…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: EARLY_PHASE1 • Sponsor: Atridia Pty Ltd. • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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New heart scan aims to predict silent strokes
Knowledge-focused CompletedThis study tested a new imaging method to measure slow-moving blood inside the heart of people with weakened heart muscle. Researchers wanted to see if this blood stagnation is linked to having silent strokes or small blood clots in the heart. The goal is to better understand who…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Sponsor: Hospital General Universitario Gregorio Marañon • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:25 UTC