HYPERTROPHIC CARDIOMYOPATHY
Clinical trials for HYPERTROPHIC CARDIOMYOPATHY explained in plain language.
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Heart drug mavacamten tested for Long-Term safety in 314 patients
Disease control CompletedThis study looked at the long-term safety of the drug mavacamten in 314 adults with hypertrophic cardiomyopathy, a condition where the heart muscle thickens. Participants had already completed earlier studies of the drug. The main goal was to track side effects over time, not to …
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: PHASE2, PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated May 17, 2026 00:51 UTC
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Can a Copper-Binding drug shrink an overgrown heart?
Disease control CompletedThis study tested a drug called trientine in 154 adults with hypertrophic cardiomyopathy, a condition where the heart muscle becomes abnormally thick. Participants took either trientine or a placebo daily for 12 months. The goal was to see if the drug could reduce heart muscle th…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: PHASE2 • Sponsor: Manchester University NHS Foundation Trust • Aim: Disease control
Last updated May 04, 2026 16:31 UTC
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New heart drug candidate passes first safety check in healthy volunteers
Knowledge-focused CompletedThis study looked at how safe a new drug called HRS-1893 is and how the body handles it. Twenty healthy adults took a single dose by mouth. The goal was to gather basic information before testing the drug in people with hypertrophic cardiomyopathy, a heart muscle disease.
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: EARLY_PHASE1 • Sponsor: Atridia Pty Ltd. • Aim: Knowledge-focused
Last updated May 17, 2026 00:50 UTC
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Heart scans may reveal hidden stroke risk
Knowledge-focused CompletedThis study looked at 258 adults with different types of heart muscle disease (cardiomyopathy) to see if special heart imaging could predict stroke or silent brain damage. Researchers measured blood flow inside the heart using ultrasound and MRI scans. The goal was to find links b…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Sponsor: Hospital General Universitario Gregorio Marañon • Aim: Knowledge-focused
Last updated May 17, 2026 00:49 UTC
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Kidney function may affect heart drug dosing – new study completed
Knowledge-focused CompletedThis study tested how the drug HRS-1893 is processed in people with mild or moderate kidney problems compared to healthy volunteers. The goal was to see if kidney function changes drug levels in the body, helping doctors recommend the right dose for patients with hypertrophic car…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: PHASE1 • Sponsor: Shandong Suncadia Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Tiny heart study tests which defibrillator is safer for thick heart muscle
Knowledge-focused CompletedThis pilot study looked at whether a larger trial is possible to compare two types of implantable defibrillators (under-the-skin vs traditional wire) in 5 people with hypertrophic cardiomyopathy who need a defibrillator but not a pacemaker. The main goals were to see how many peo…
Matched conditions: HYPERTROPHIC CARDIOMYOPATHY
Phase: NA • Sponsor: Barts & The London NHS Trust • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC