Could a Copper-Binding drug shrink thickened heart muscle?
NCT ID NCT04706429
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether the drug trientine can reduce heart muscle thickening and improve exercise ability in people with hypertrophic cardiomyopathy (HCM), a condition where the heart muscle becomes abnormally thick. 154 adults with HCM took either trientine or a placebo for 12 months. The main goal was to see if the drug could shrink the heart muscle and improve heart function.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Liverpool Heart and Chester Hospital NHS Foundation Trust
Liverpool, L14 3PE, United Kingdom
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Manchester University NHS Foundation Trust
Manchester, M23 9LT, United Kingdom
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NHS Grampian
Aberdeen, AB25 2ZN, United Kingdom
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Northumbria Healthcare NHS Foundation Trust
North Shields, NE29 8NH, United Kingdom
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Oxford University Hospitals NHS Foundation Trust
Oxford, OX3 9DU, United Kingdom
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Royal Brompton and Harefield NHS Foundation Trust
London, SW3 6NP, United Kingdom
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University Hospitals of Leicester NHS Foundation Trust
Leicester, LE3 9QP, United Kingdom