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Heart drug mavacamten tested for long-term safety in HCM patients

NCT ID NCT03723655

Completed Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at the long-term safety of the drug mavacamten in adults with hypertrophic cardiomyopathy, a condition where the heart muscle thickens. About 314 people who had already finished earlier studies took part. The goal was to track side effects over time, not to cure the disease.

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Conditions

The condition(s) this trial relates to.

hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTROPHIC CARDIOMYOPATHY NON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY

Contacts and locations

Locations

  • Local Institution - 0001

    Brussels, 1070, Belgium

  • Local Institution - 0002

    Aalst, 9300, Belgium

  • Local Institution - 0003

    Edegem, 2650, Belgium

  • Local Institution - 0009

    Prague, 140 21, Czechia

  • Local Institution - 0010

    Prague, 128 08, Czechia

  • Local Institution - 0011

    Aarhus, 8000, Denmark

  • Local Institution - 0012

    Frederiksberg, 2000, Denmark

  • Local Institution - 0013

    Odense, 5000, Denmark

  • Local Institution - 0014

    Nantes, 44093, France

  • Local Institution - 0015

    Toulouse, 31059, France

  • Local Institution - 0016

    Paris, 75015, France

  • Local Institution - 0017

    Paris, 75013, France

  • Local Institution - 0018

    Dresden, 01277, Germany

  • Local Institution - 0019

    Göttingen, 37075, Germany

  • Local Institution - 0020

    Bad Nauheim, 61231, Germany

  • Local Institution - 0021

    Heidelberg, 69120, Germany

  • Local Institution - 0022

    Ramat Gan, 52621, Israel

  • Local Institution - 0023

    Safed, 13100, Israel

  • Local Institution - 0024

    Petah Tikva, 4941492, Israel

  • Local Institution - 0025

    Rehovot, 76100, Israel

  • Local Institution - 0026

    Tel Aviv, 6423906, Israel

  • Local Institution - 0027

    Jerusalem, 9112001, Israel

  • Local Institution - 0028

    Florence, 50139, Italy

  • Local Institution - 0029

    Maastricht, 6229 HX, Netherlands

  • Local Institution - 0030

    Rotterdam, 3015 CE, Netherlands

  • Local Institution - 0031

    Poznan, 61-848, Poland

  • Local Institution - 0032

    Warsaw, 04-628, Poland

  • Local Institution - 0033

    Katowice, 40-555, Poland

  • Local Institution - 0034

    Krakow, 31-501, Poland

  • Local Institution - 0035

    Lisbon, 1500-650, Portugal

  • Local Institution - 0036

    Almada, 2805-267, Portugal

  • Local Institution - 0037

    El Palmar, 30120, Spain

  • Local Institution - 0038

    A Coruña, 15006, Spain

  • Local Institution - 0039

    Majadahonda, 28222, Spain

  • Local Institution - 0040

    Madrid, 28034, Spain

  • Local Institution - 0041

    Seville, 41009, Spain

  • Local Institution - 0042

    London, W1G 8PH, United Kingdom

  • Local Institution - 0043

    New Haven, Connecticut, 06520-8017, United States

  • Local Institution - 0044

    Portland, Oregon, 97239, United States

  • Local Institution - 0045

    Scottsdale, Arizona, 85259, United States

  • Local Institution - 0046

    Philadelphia, Pennsylvania, 19104, United States

  • Local Institution - 0047

    Durham, North Carolina, 27710, United States

  • Local Institution - 0048

    St Louis, Missouri, 63110, United States

  • Local Institution - 0049

    Iowa City, Iowa, 52242, United States

  • Local Institution - 0050

    Chicago, Illinois, 60611, United States

  • Local Institution - 0051

    Ann Arbor, Michigan, 48109, United States

  • Local Institution - 0052

    Cincinnati, Ohio, 45267, United States

  • Local Institution - 0053

    Charlottesville, Virginia, 22903, United States

  • Local Institution - 0054

    Boston, Massachusetts, 02115, United States

  • Local Institution - 0055

    Houston, Texas, 77030, United States

  • Local Institution - 0056

    New York, New York, 10032, United States

  • Local Institution - 0057

    Houston, Texas, 77030, United States

  • Local Institution - 0058

    Los Angeles, California, 90027, United States

  • Local Institution - 0059

    Richmond, Virginia, 23298, United States

  • Local Institution - 0060

    New York, New York, 10016, United States

  • Local Institution - 0061

    Dallas, Texas, 75390, United States

  • Local Institution - 0062

    Salt Lake City, Utah, 84112, United States

  • Local Institution - 0063

    Stanford, California, 94305, United States

  • Local Institution - 0064

    Pittsburgh, Pennsylvania, 15213, United States

  • Local Institution - 0065

    Seattle, Washington, 98195, United States

  • Local Institution - 0066

    San Francisco, California, 94143, United States

  • Local Institution - 0067

    Jacksonville, Florida, 32224, United States

  • Local Institution - 0068

    Bethlehem, Pennsylvania, 18015, United States

  • Local Institution - 0070

    Indianapolis, Indiana, 46260, United States

  • Local Institution - 0071

    Charlotte, North Carolina, 28204, United States

  • Local Institution - 0072

    Murray, Utah, 84107-5701, United States

  • Local Institution - 0073

    Memphis, Tennessee, 38104, United States

  • Local Institution - 0074

    Grand Rapids, Michigan, 49503, United States

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