HYPERTRIGLYCERIDEMIA

This study tested a drug called olezarsen in 154 adults with high triglycerides (a type of blood fat) and either heart disease or very high triglycerides. Participants received injections of the drug or a placebo for up to 12 months. The main goal was to see if the drug could low…

This Phase 3 study tested a drug called olezarsen in 1,478 people with very high triglycerides (a type of blood fat) and either heart disease or a high risk for it. Participants received either olezarsen or a placebo as a shot under the skin. The main goal was to see if olezarsen…

This early-stage study tested a new medicine called ARO-ANG3 in 93 people, including healthy volunteers and patients with high cholesterol or high triglycerides. The main goal was to check if the drug is safe and how the body processes it. This research helps determine if the dru…

This early-stage study tested a new medicine called ARO-APOC3 in healthy volunteers and people with severely high triglycerides or a rare genetic condition called familial chylomicronemia syndrome. The main goal was to check safety and how the drug moves through the body. The stu…

This study tested whether the drug RDX-002 can lower high blood fat levels in people who recently stopped taking weight-loss medications like semaglutide or tirzepatide. Sixty-eight adults who had lost at least 10% of their body weight on those drugs took either RDX-002 or a plac…

This Phase 3 trial tested a new combination drug called Cipros 10 against the standard statin Crestor in 146 adults with dyslipidemia (high cholesterol and triglycerides). The goal was to see if Cipros 10 could lower triglyceride levels more effectively. Participants took one pil…

This study tested a new medicine, MAR001, in 55 adults with high triglycerides (a type of fat in the blood) and metabolic problems. The main goal was to see if the drug is safe and tolerable. Researchers also checked if it could lower triglyceride levels. The study was completed …

This study tested whether low-dose omega-3 supplements (250 mg EPA per day) can improve cholesterol and inflammation in overweight or obese adults with high triglycerides. Forty participants in Chile took omega-3 or a placebo for six weeks each in a crossover design. The goal was…

This study looked at whether taking fish oil and doing high-intensity interval training (HIIT) could lower inflammation in people who are overweight or obese. Researchers measured changes in blood markers of inflammation and metabolism over 10 weeks. The goal was to see if the co…

This early-phase study tested a single dose of VSA003 in 36 healthy Chinese adults to see if it is safe and how the body handles it. The drug aims to help control high cholesterol and triglycerides. Participants received either VSA003 or a placebo, and researchers monitored for s…