HUNTINGTON'S DISEASE
Clinical trials for HUNTINGTON'S DISEASE explained in plain language.
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New spinal injection aims to tame Huntington's
Disease control Recruiting nowThis early-stage study tests an experimental drug called ALN-HTT02 in 66 adults with Huntington's disease. The drug is given as a single injection into the spine to see if it is safe and how it affects the body. The goal is to reduce levels of the harmful protein that causes the …
Matched conditions: HUNTINGTON'S DISEASE
Phase: PHASE1 • Sponsor: Alnylam Pharmaceuticals • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Hope for Huntington's: new drug aims to slow decline in major trial
Disease control Recruiting nowThis study tests whether the drug pridopidine can slow the worsening of Huntington's disease (HD) in adults. About 400 participants will take either pridopidine or a placebo twice daily for one year, then everyone can receive pridopidine for two more years. The goal is to see if …
Matched conditions: HUNTINGTON'S DISEASE
Phase: PHASE3 • Sponsor: Prilenia • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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New drug SRP-1005 takes first step against Huntington's
Disease control Recruiting nowThis study tests a new drug called SRP-1005 in 32 adults with Huntington's disease. It is the first time this drug is being tested in humans, so the main goal is to check safety and how the body processes the drug. Participants will receive either SRP-1005 or a placebo by injecti…
Matched conditions: HUNTINGTON'S DISEASE
Phase: PHASE1 • Sponsor: Sarepta Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New PET tracer aims to spot Huntington's protein clumps in living brains
Diagnosis Recruiting nowThis early-stage study tests a new radioactive tracer called [11C]CHDI-00491009 to see if it can safely and accurately detect harmful protein clumps (mutant huntingtin) in the brains of people with Huntington's disease. The study involves 27 participants, including healthy volunt…
Matched conditions: HUNTINGTON'S DISEASE
Phase: EARLY_PHASE1 • Sponsor: CHDI Foundation, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 11:01 UTC
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Can video games help Huntington's patients move and think better?
Symptom relief Recruiting nowThis study compares two types of exercise-video game (exergame) programs for people with Huntington's disease. One program mixes physical and mental exercises together, while the other does them separately. Researchers want to see which approach improves balance, thinking, and da…
Matched conditions: HUNTINGTON'S DISEASE
Phase: NA • Sponsor: University Hospital, Angers • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Brain scan tracer could reveal hidden signs of psychosis in Parkinson's
Knowledge-focused Recruiting nowThis study uses a special PET scan tracer, [18F]MH.MZ, to measure serotonin 2A receptors in the brains of people with neurodegenerative diseases like Parkinson's. Researchers want to see if these receptors differ between patients with psychosis and healthy people of the same age.…
Matched conditions: HUNTINGTON'S DISEASE
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Massive hunt for Huntington's clues: 2,500 volunteers needed for spinal fluid study
Knowledge-focused Recruiting nowThis study aims to collect cerebrospinal fluid and blood samples from 2,500 people at various stages of Huntington's disease, as well as healthy volunteers. The goal is to find biological markers that can help researchers develop new treatments. Participants must be between 11 an…
Matched conditions: HUNTINGTON'S DISEASE
Sponsor: University College, London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC