HUNTINGTON'S DISEASE
Clinical trials for HUNTINGTON'S DISEASE explained in plain language.
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New Brain-Injected drug aims to target root cause of Huntington's disease
Disease control Recruiting nowThis is an early-stage study to test the safety and effects of a new drug called ALN-HTT02 for Huntington's disease. The drug is injected into the spinal fluid to try to lower the harmful protein that causes the disease. The study will involve 66 adults with mid-stage Huntington'…
Matched conditions: HUNTINGTON'S DISEASE
Phase: PHASE1 • Sponsor: Alnylam Pharmaceuticals • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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First human test of new Huntington's disease drug begins
Disease control Recruiting nowThis is the first study in humans testing RG6496, a new drug for Huntington's disease. Researchers will give single, increasing doses to 40 people who carry the Huntington's disease gene to check if it's safe and well-tolerated. The study will also measure if the drug reduces the…
Matched conditions: HUNTINGTON'S DISEASE
Phase: PHASE1 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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First human test of brain scan to track Huntington's disease protein
Knowledge-focused Recruiting nowThis study is testing a new brain imaging tracer to see if it can measure the harmful mutant huntingtin protein that builds up in the brains of people with Huntington's disease. Researchers will use PET scans to compare 27 participants, including healthy volunteers and people at …
Matched conditions: HUNTINGTON'S DISEASE
Phase: EARLY_PHASE1 • Sponsor: CHDI Foundation, Inc. • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Major study seeks spinal fluid clues to fight Huntington's disease
Knowledge-focused Recruiting nowThis study aims to collect spinal fluid and blood samples from 2,500 people at different stages of Huntington's disease. The goal is to find biological markers that can help researchers understand the disease better and develop new treatments. Participants will have annual visits…
Matched conditions: HUNTINGTON'S DISEASE
Sponsor: University College, London • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Scientists search for Huntington's disease clues in young brains
Knowledge-focused Recruiting nowThis study aims to understand if Huntington's disease begins with abnormal brain development, not just later degeneration. Researchers will use brain scans and cognitive tests to compare children and young adults (ages 6-30) who are at genetic risk for the disease with those who …
Matched conditions: HUNTINGTON'S DISEASE
Sponsor: Peggy C Nopoulos • Aim: Knowledge-focused
Last updated Mar 17, 2026 12:55 UTC