Massive hunt for Huntington's clues: 2,500 volunteers needed for spinal fluid study

NCT ID NCT02855476

Recruiting now Knowledge-focused Sponsor: University College, London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to collect cerebrospinal fluid and blood samples from 2,500 people at various stages of Huntington's disease, as well as healthy volunteers. The goal is to find biological markers that can help researchers develop new treatments. Participants must be between 11 and 75 years old and, except for family or community controls, have had a genetic test for Huntington's.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could identify key biological markers that help develop new treatments for Huntington's disease.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to a therapy, and results depend on participant diversity and sample quality.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Huntington disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HUNTINGTON'S DISEASE

Contacts and locations

Locations

Birmingham Huntingtons Disease Clinic
RECRUITING

Birmingham, West Midlands, B15 2 FG, United Kingdom
Cambridge University Hospitals NHS Foundation Trust
RECRUITING

Cambridge, CB2 0PY, United Kingdom
Cardiff University
RECRUITING

Cardiff, CF24 4HQ, United Kingdom
Cenexel
RECRUITING

Englewood, Colorado, United States
Centre Hospitalier Universitaire d'Angers
RECRUITING

Angers, 49000, France
Centre for Movement Disorders
COMPLETED

Toronto, Ontario, M3B 2S7, Canada
Cruces University Hospital
ACTIVE_NOT_RECRUITING

Bilbao, Biscay, 48903, Spain
Dresden University
RECRUITING

Dresden, Saxony, 01307, Germany
Fife Health Board - Whyteman's Brae Hospital
ACTIVE_NOT_RECRUITING

Kirkcaldy, KY1 2ND, United Kingdom
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
ACTIVE_NOT_RECRUITING

Milan, 20133, Italy
George Huntington Institute
RECRUITING

Münster, 48149, Germany
Georgetown University
RECRUITING

Washington D.C., District of Columbia, 20057, United States
Glasgow Clinical Research Facility
RECRUITING

Glasgow, Scotland, G51 4TF, United Kingdom
Gulbenkian Institute of Molecular Medicine
RECRUITING

Lisbon, 1649-028, Portugal
Hospital de Sant Pau
RECRUITING

Barcelona, 08041, Spain
Institute of Psychiatry and Neurology
ACTIVE_NOT_RECRUITING

Warsaw, 02-957, Poland
John Hopkins University
RECRUITING

Baltimore, Maryland, 21287, United States
Kbo-Isar-Amper-Klinikum Taufkirchen (Vils)
RECRUITING

Taufkirchen, 84416, Germany
Le Centre Hospitalier Universitaire de Bordeaux
RECRUITING

Bordeaux, 33076, France
Leeds Teaching Hospital Trust
RECRUITING

Leeds, LS7 4SA, United Kingdom
Lega Italiana Ricera Huntington
RECRUITING

Rome, 00185, Italy
NZ Brain Research Institute
RECRUITING

Christchurch, Canterbury, 8011, New Zealand
North Bristol NHS Trust
ACTIVE_NOT_RECRUITING

Bristol, BS10 5NB, United Kingdom
North York General Hospital
RECRUITING

Toronto, Ontario, M2K 1E1, Canada
Oxford University Hospitals NHS Foundation Trust
RECRUITING

Oxford, OX3 9DU, United Kingdom
Ramón y Cajal Universitary Hospital
RECRUITING

Madrid, 28034, Spain
Royal Devon & Exeter NHS Foundation Trust
RECRUITING

Exeter, Devon, EX2 5DW, United Kingdom
St George's University Of London
RECRUITING

London, SW17 0RE, United Kingdom
St Josef And Elisabeth Hospital
RECRUITING

Bochum, 44791, Germany
The Ottawa Hospital
RECRUITING

Ottawa, Ontario, K1Y 4E9, Canada
The University of Auckland
RECRUITING

Grafton, Auckland, 1023, New Zealand
The Walton Centre NHS Foundation Trust
RECRUITING

Liverpool, L9 7LJ, United Kingdom
University College London Hospitals NHS Foundation Trust
RECRUITING

London, NW1 2PG, United Kingdom
University Hospital Ulm
RECRUITING

Ulm, Baden-Wurttemberg, 89081, Germany
University Hospital of Erlangen
RECRUITING

Erlangen, 91054, Germany
University Hospitals Plymouth NHS Trust
RECRUITING

Plymouth, PL6 5FP, United Kingdom
University of British Columbia, The Centre for Huntingtons Disease
ACTIVE_NOT_RECRUITING

Vancouver, British Columbia, V6T 2B5, Canada
University of Texas Health Science Center
RECRUITING

Houston, Texas, 77030, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37212, United States
Wake Forest University
COMPLETED

Winston-Salem, North Carolina, 27109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.