New spinal injection aims to slow Huntington's brain damage

NCT ID NCT06585449

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 27 times

Summary

This study tests a new drug called ALN-HTT02 in 66 adults with early-stage Huntington's disease. The drug is given as a single injection into the spine to see if it is safe and how it affects the body. Researchers will also measure levels of the harmful huntingtin protein in spinal fluid. The goal is to find a treatment that controls the disease, not cure it.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HUNTINGTON'S DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Trial Site

    RECRUITING

    Edmonton, T6G 2B7, Canada

  • Clinical Trial Site

    RECRUITING

    Montreal, H2W 1T8, Canada

  • Clinical Trial Site

    RECRUITING

    Ottawa, K1Y4E9, Canada

  • Clinical Trial Site

    RECRUITING

    Vancouver, V6T 2B5, Canada

  • Clinical Trial Site

    NOT_YET_RECRUITING

    Berlin, 10117, Germany

  • Clinical Trial Site

    RECRUITING

    Bochum, 44791, Germany

  • Clinical Trial Site

    RECRUITING

    Bonn, 53127, Germany

  • Clinical Trial Site

    RECRUITING

    Dresden, 01307, Germany

  • Clinical Trial Site

    RECRUITING

    Münster, 48149, Germany

  • Clinical Trial Site

    RECRUITING

    Taufkirchen, 84416, Germany

  • Clinical Trial Site

    RECRUITING

    Ulm, 89081, Germany

  • Clinical Trial Site

    RECRUITING

    Birmingham, B15 2TT, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Cambridge, CB2 0PY, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Cardiff, CF103AX, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Greater Manchester, M13 9WL, United Kingdom

  • Clinical Trial Site

    RECRUITING

    London, WC1N 3BG, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Plymouth, PL6 8DH, United Kingdom

Conditions

Explore the condition pages connected to this study.