New spinal injection aims to tame Huntington's

NCT ID NCT06585449

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests an experimental drug called ALN-HTT02 in 66 adults with Huntington's disease. The drug is given as a single injection into the spine to see if it is safe and how it affects the body. The goal is to reduce levels of the harmful protein that causes the disease, but this is not a cure—it aims to control the disease over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Huntington disease neurodegenerative disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Trial Site

    RECRUITING

    Edmonton, T6G 2B7, Canada

  • Clinical Trial Site

    RECRUITING

    Montreal, H2W 1T8, Canada

  • Clinical Trial Site

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    Ottawa, K1Y4E9, Canada

  • Clinical Trial Site

    RECRUITING

    Vancouver, V6T 2B5, Canada

  • Clinical Trial Site

    RECRUITING

    Berlin, 10117, Germany

  • Clinical Trial Site

    RECRUITING

    Bochum, 44791, Germany

  • Clinical Trial Site

    RECRUITING

    Bonn, 53127, Germany

  • Clinical Trial Site

    RECRUITING

    Dresden, 01307, Germany

  • Clinical Trial Site

    RECRUITING

    Münster, 48149, Germany

  • Clinical Trial Site

    RECRUITING

    Taufkirchen, 84416, Germany

  • Clinical Trial Site

    RECRUITING

    Ulm, 89081, Germany

  • Clinical Trial Site

    RECRUITING

    Birmingham, B15 2TT, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Cambridge, CB2 0PY, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Cardiff, CF103AX, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Greater Manchester, M13 9WL, United Kingdom

  • Clinical Trial Site

    RECRUITING

    London, WC1N 3BG, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

  • Clinical Trial Site

    RECRUITING

    Plymouth, PL6 8DH, United Kingdom